Elliott C T, McEvoy J D, McCaughey W J, Shortt D H, Crooks S R
Residue Laboratory, Veterinary Science Division, Stormont, Belfast, UK.
Analyst. 1993 Apr;118(4):447-8. doi: 10.1039/an9931800447.
The use of the beta-agonist clenbuterol (CBL) as a growth promoter has been outlawed in European meat production. The detection of its illegal use is dependent on CBL residues persisting in animal tissues for longer than the withdrawal times given by abusers. A comparison of urine, bile and liver matrices indicated that analysis of the liver offered the best possibility for CBL detection. However, an experimental study showed that CBL detection following withdrawal could be further extended (up to 56 d) if the retina was used as the target tissue. Analysis of 703 retina and liver samples from cattle suspected of CBL medication revealed that 96 cattle had CBL residues present in their retinas, only 46 of these were liver positive. There were no instances of liver CBL residues being detected without the associated retina also being positive.
在欧洲肉类生产中，使用β-激动剂克伦特罗（CBL）作为生长促进剂已被认定为非法行为。对其非法使用的检测取决于CBL在动物组织中的残留时间长于滥用者规定的停药期。尿液、胆汁和肝脏基质的比较表明，对肝脏进行分析为检测CBL提供了最佳可能性。然而，一项实验研究表明，如果将视网膜用作目标组织，停药后CBL的检测时间可以进一步延长（长达56天）。对703份疑似使用CBL药物的牛的视网膜和肝脏样本进行分析后发现，96头牛的视网膜中存在CBL残留，其中只有46头牛的肝脏检测呈阳性。没有出现仅肝脏CBL残留呈阳性而相关视网膜检测不呈阳性的情况。
