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用于测定胸腰椎骨矿物质含量的外侧双能X线吸收法的准确性:一项体外研究。

Accuracy of lateral dual energy X-ray absorptiometry for the determination of bone mineral content in the thoracic and lumbar spine: an in vitro study.

作者信息

Edmondston S J, Singer K P, Price R I, Breidahl P D

机构信息

Department of Radiology, Royal Perth Hospital, Western Australia.

出版信息

Br J Radiol. 1993 Apr;66(784):309-13. doi: 10.1259/0007-1285-66-784-309.

DOI:10.1259/0007-1285-66-784-309
PMID:8495284
Abstract

Lateral scanning with dual energy X-ray absorptiometry (DXA) was undertaken on 153 thoracic and lumbar vertebral bodies from nine individuals (mean age 67; range 34-92 years) to establish their bone mineral content (BMC). All specimens were subsequently de-fatted and ashed to compare ash weight with BMC of the T1 to L5 segments. Linear regression analysis indicated a higher correlation between BMC and measured ash weights for each vertebral column (range: r = 0.97-0.99), with error for all vertebrae tested showing a standard error of 0.40 g, or 10.8%. For the L2-4 segments the accuracy error was 0.50 g or 7.9%. In both cases there was a mean trend towards underestimation of ash weight. Mean BMC values of the T1 to T5 segments were similar before a progressive increase caudally. These data affirm the utility of DXA for determining bone mineral content in the vertebral column across wide ranges of age, and segmental and bone density.

摘要

对9名个体(平均年龄67岁;年龄范围34 - 92岁)的153个胸椎和腰椎椎体进行了双能X线吸收法(DXA)侧位扫描,以确定其骨矿物质含量(BMC)。随后对所有标本进行脱脂和灰化处理,以比较T1至L5节段的灰重与BMC。线性回归分析表明,每个脊柱的BMC与测量的灰重之间具有更高的相关性(范围:r = 0.97 - 0.99),所有测试椎体的误差显示标准误差为0.40 g,即10.8%。对于L2 - 4节段,准确误差为0.50 g或7.9%。在这两种情况下,均存在灰重平均被低估的趋势。T1至T5节段的平均BMC值在尾侧逐渐增加之前相似。这些数据证实了DXA在确定不同年龄范围、节段和骨密度的脊柱骨矿物质含量方面的实用性。

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