Alloway J A, Cupps T R
Department of Internal Medicine, Georgetown University Medical Center, Washington, DC 20007-2197.
J Rheumatol. 1993 Apr;20(4):752-4.
Wegener's granulomatosis (WG) is frequently associated with retroorbital involvement, which typically responds slowly to the standard therapy of oral corticosteroids and cytotoxic agents. We describe the case of a 61-year-old man with WG, who developed marked retroorbital granulomatous inflammatory tissue and experienced a dramatic clinical and radiographic response to the administration of high dose intravenous (iv) methylprednisolone. We believe that high dose iv methylprednisolone may have distinct advantages over standard therapies in the treatment of retroorbital WG.
韦格纳肉芽肿（WG）常伴有眶后受累，其对口服糖皮质激素和细胞毒性药物的标准治疗通常反应缓慢。我们描述了一名61岁患有WG的男性病例，该患者出现了明显的眶后肉芽肿性炎症组织，并且在给予大剂量静脉注射甲泼尼龙后临床和影像学表现均有显著改善。我们认为，在治疗眶后型WG方面，大剂量静脉注射甲泼尼龙可能比标准治疗具有明显优势。
