Echevarría S, Martínez J, Fariñas M C, Sampedro J R, Sampedro I, Agüero R
Departamento de Medicina Interna, H. U. Marqués de Valdecillo, Santander.
Rev Clin Esp. 1993 Apr;192(6):274-9.
In our setting, patients infected by human immunodeficiency virus (HIV) show a high rate of tuberculosis infections which manifestations depend on the level of immunodeficiency reached.
Clinical, radiological and evolutive characteristics are discussed of 100 diagnosed tuberculosis in seropositive patients during a time span of 52 months, relating them to the number of CD4 detected.
Tuberculosis pulmonary forms (65%) were more frequent than extra-pulmonary ones (35%) even in the advanced phases of the disease due to HIV, even tough the latter tend to cluster in patients with less than 200 CD1/mm. An unspecific febrile syndrome, normal results on simple radiological exploration and the difficulty to obtain diagnostic samples are facts which often delay the diagnosis.
Even tough the extra-pulmonary forms are more frequent in the last stages of the disease due to HIV, in our setting there is still a high incidence of pulmonary forms in all stages.
在我们的研究环境中，感染人类免疫缺陷病毒（HIV）的患者结核病感染率很高，其表现取决于所达到的免疫缺陷水平。
讨论了52个月内100例血清学阳性患者确诊结核病的临床、放射学和演变特征，并将其与检测到的CD4数量相关联。
即使在由HIV引起的疾病晚期，肺结核形式（65%）也比肺外结核形式（35%）更常见，尽管后者往往集中在CD4低于200/立方毫米的患者中。非特异性发热综合征、简单放射学检查结果正常以及难以获取诊断样本等情况常常会延迟诊断。
尽管肺外结核形式在由HIV引起的疾病后期更为常见，但在我们的研究环境中，所有阶段肺结核形式的发病率仍然很高。
