Chew P C, Loganath A, Peh K L, Chow W P, Gunasegaram R, Ratnam S S
Department of Obstetrics and Gynaecology, National University Hospital, Singapore.
Arch Androl. 1993 May-Jun;30(3):165-70. doi: 10.3109/01485019308987752.
In an attempt to determine whether human spermatozoa contain steroid hormones, the immunoreactive levels of progesterone, testosterone, and estradiol-17 beta were measured in the extracts of sonicated specimens of sperm obtained as ejaculates from husbands of infertile couples (n = 67, age 26-44 years). In the range of sperm concentration between 3.0 and 869.6 million per ejaculate (143.2 +/- 13.6 mean +/- SEM), the concentrations were as follows: progesterone 127.3-6685.4 fmol/ml (1434.5 +/- 178.6), testosterone 98.3-2219.1 fmol/ml (611.6 +/- 49.0), and estradiol-17 beta 33.0-678.1 fmol/ml (206.9 +/- 19.7). Using Pearson's correlation coefficient, the steroid hormone levels correlated significantly with the total sperm number (p < .02). The spermatozoa contained small but measurable amounts of the sex steroids.
为了确定人类精子是否含有类固醇激素，对从不育夫妇的丈夫（n = 67，年龄26 - 44岁）射精获得的精子超声处理标本提取物中的孕酮、睾酮和雌二醇 - 17β的免疫反应水平进行了测量。在每次射精精子浓度介于3.0至8.696亿个之间（平均1.432亿个±1360万个，均值±标准误）的范围内，其浓度如下：孕酮127.3 - 6685.4 fmol/ml（1434.5±178.6），睾酮98.3 - 2219.1 fmol/ml（611.6±49.0），以及雌二醇 - 17β 33.0 - 678.1 fmol/ml（206.9±19.7）。使用皮尔逊相关系数，类固醇激素水平与精子总数显著相关（p < 0.02）。精子含有少量但可测量的性类固醇。
