强迫症的单光子发射计算机断层扫描：一项初步研究。
Single photon emission computerized tomography in obsessive compulsive disorder: a preliminary study.
作者信息
Adams B L, Warneke L B, McEwan A J, Fraser B A
机构信息
Department of Psychiatry, University of Alberta, Edmonton, Canada.
出版信息
J Psychiatry Neurosci. 1993 May;18(3):109-12.
Abstract
Patterns of cerebral perfusion in patients with obsessive compulsive disorder were evaluated using single photon emission computerized tomography. Eleven patients, who satisfied the DSM-III-R criteria and Research Diagnostic Criteria for the disorder, were evaluated using the distribution of 99m-Tc-HMPAO as a radiotracer. The Yale-Brown Obsessive Compulsive Scale was administered to each patient to assess the severity of their symptoms. The images obtained were evaluated qualitatively and semi-quantitatively by a physician in nuclear medicine who was blind to the patients' diagnoses. Eight of the 11 patients demonstrated asymmetric perfusion of the basal ganglia; the left side showed impaired perfusion in six patients.
摘要
采用单光子发射计算机断层扫描评估强迫症患者的脑灌注模式。对11名符合DSM-III-R标准和该疾病研究诊断标准的患者，使用99m-Tc-HMPAO的分布作为放射性示踪剂进行评估。对每位患者进行耶鲁-布朗强迫症量表评估以确定其症状的严重程度。由一名对患者诊断不知情的核医学医生对获得的图像进行定性和半定量评估。11名患者中有8名表现出基底神经节灌注不对称；6名患者左侧灌注受损。
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