Ward J B, Siojo L G, Waller S G
Department of Ophthalmology, Primary Care, and Flight Medicine, 13th Air Force Medical Center, Clark Air Base, Republic of the Philippines.
Cornea. 1993 May;12(3):216-21. doi: 10.1097/00003226-199305000-00006.
Epidemics of viral conjunctivitis are a major public health problem in the Far East. No treatment has been shown to shorten the duration of illness. We studied the clinical course of epidemic keratoconjunctivitis in 74 patients during an outbreak of nearly 3,000 cases in late 1988 at a U.S. military base in the Philippines. Patients were randomly assigned to treatment with trifluridine, dexamethasone, or artificial tears, and examined in a double-masked fashion. There was no significant difference between the results of the three treatments. No bacterial cultures were positive. The prompt use of patient isolation, identification of nonadenoviral red eyes, and symptomatic treatment without steroids, antiviral, or antibiotic medication is recommended in cases of epidemic keratoconjunctivitis. This is the largest series of cases of epidemic keratoconjunctivitis with laboratory confirmation reported from the Philippines.
病毒性结膜炎的流行是远东地区的一个主要公共卫生问题。尚无治疗方法能缩短病程。我们对1988年末在菲律宾一个美国军事基地爆发的近3000例病例中的74例流行性角膜结膜炎患者的临床病程进行了研究。患者被随机分配接受三氟尿苷、地塞米松或人工泪液治疗，并以双盲方式进行检查。三种治疗结果之间无显著差异。细菌培养均为阴性。对于流行性角膜结膜炎病例，建议迅速采取患者隔离措施，识别非腺病毒引起的红眼病，并进行无类固醇、抗病毒或抗生素药物的对症治疗。这是菲律宾报告的经实验室确诊的最大系列流行性角膜结膜炎病例。
