Pradimicins T1 and T2, new antifungal antibiotics produced by an actinomycete. I. Taxonomy, production, isolation, physico-chemical and biological properties.
作者信息
Furumai T, Hasegawa T, Kakushima M, Suzuki K, Yamamoto H, Yamamoto S, Hirano M, Oki T
机构信息
Bristol-Myers Squibb Research Institute, Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1993 Apr;46(4):589-97. doi: 10.7164/antibiotics.46.589.
PMID:8501001
Abstract
Pradimicins T1 and T2, new members of the pradimicin family of antibiotics, were produced by an actinomycete strain AA3798. Pradimicin T1 exhibited potent activity against a wide spectrum of fungi in vitro and demonstrated efficacy against systemic Candida albicans and Aspergillus fumigatus infections in mice.
摘要
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