Tverdal A, Thelle D, Stensvold I, Leren P, Bjartveit K
National Health Screening Service, Oslo, Norway.
J Clin Epidemiol. 1993 May;46(5):475-87. doi: 10.1016/0895-4356(93)90025-v.
A total of 44,290 men and 24,535 women aged 35-49 have been followed with respect to different causes of death during 13.3 years on average. A detailed history of smoking, together with other important risk factors, were recorded in a standardized way. Compared with the classical American and British studies, the excess mortality for the smokers was largely the same for the majority of causes. The exceptions were cerebrovascular mortality and suicides and accidents, which were more strongly related to smoking in this study. Furthermore, men who smoked only pipe, had nearly the same coronary heart disease mortality as men who smoked only cigarettes. The same applies to lung cancer mortality. Among men who had quit cigarette smoking, the coronary heart disease mortality decreased with time since quitting to almost the level of the never cigarette smokers after 5 years or more.
共有44290名35至49岁的男性和24535名35至49岁的女性接受了平均13.3年的随访,观察不同的死亡原因。吸烟的详细历史以及其他重要风险因素均以标准化方式记录。与经典的美国和英国研究相比,吸烟者的超额死亡率在大多数死因上基本相同。例外情况是脑血管疾病死亡率、自杀和意外事故,在本研究中这些与吸烟的关联更为密切。此外,仅抽斗烟的男性的冠心病死亡率与仅吸卷烟的男性几乎相同。肺癌死亡率也是如此。在已戒烟的男性中,冠心病死亡率随着戒烟时间的推移而下降,5年或更长时间后降至几乎与从不吸烟者相同的水平。