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输精管复通术预期的最佳妊娠率是多少?

What is the best pregnancy rate that may be expected from vasectomy reversal?

作者信息

Sharlip I D

机构信息

Department of Urological Surgery, California-Pacific Medical Center, San Francisco.

出版信息

J Urol. 1993 Jun;149(6):1469-71. doi: 10.1016/s0022-5347(17)36417-0.

Abstract

Pregnancy rates after vasectomy reversal vary among different reporting surgeons. To study those patients who are most likely to achieve pregnancy after vasectomy reversal, and to eliminate the effect of variations in surgical technique and operative findings on surgical outcome, the pregnancy rate after vasectomy reversal was calculated in men who achieved completely and consistently normal postoperative semen analyses (sperm concentration 20 x 10(6)/ml. or more and sperm motility 50% or greater). Of 95 patients who met the study criteria 58 (61.1%) achieved pregnancy and 37 (30.9%) did not. Including an allowance for some patients who will achieve pregnancy beyond the study-followup, it is concluded that the maximum pregnancy probability for vasectomy reversal is approximately 67%. Failure to achieve pregnancy in approximately a third of the patients may be explained by partner infertility, epididymal dysfunction and sperm antibodies. Studies that report pregnancy chances in excess of two-thirds must have different patient demographics and/or different methods of statistical analysis.

摘要

输精管复通术后的妊娠率在不同的报告医生之间存在差异。为了研究输精管复通术后最有可能实现妊娠的患者,并消除手术技术和手术结果的差异对手术结局的影响,对术后精液分析完全且持续正常(精子浓度20×10⁶/ml或更高且精子活力50%或更高)的男性计算输精管复通术后的妊娠率。在符合研究标准的95例患者中,58例(61.1%)实现了妊娠,37例(30.9%)未实现妊娠。包括对一些在研究随访期后实现妊娠的患者的考虑,得出结论:输精管复通术的最大妊娠概率约为67%。大约三分之一的患者未能实现妊娠可能是由于配偶不孕、附睾功能障碍和精子抗体。报告妊娠机会超过三分之二的研究必定有不同的患者特征和/或不同的统计分析方法。

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