Osterlind A, Kjems E
Danish Cancer Society, Division for Cancer Epidemiology, Copenhagen.
APMIS Suppl. 1993;33:149-55.
Survival after malignant melanoma in Denmark has improved remarkably in all age groups and people of each sex over the last 30 years. During the study period 1943 87, the proportion of patients presenting with an earlier stage of disease at the time of diagnosis increased. No major change has taken place with respect to treatment. Extent of disease, age and sex exerted a steady influence on survival during the study period. Melanoma patients with localized disease had a far better survival expectancy than those with disseminated disease at the time of diagnosis. Age at time of diagnosis had a clear impact on subsequent survival, younger patients having a better prognosis than older ones. In all age groups, women had a higher relative survival rate than men.
在过去30年里,丹麦恶性黑色素瘤患者的生存率在所有年龄组和各性别中都有显著提高。在1943 - 1987年的研究期间,诊断时疾病处于早期阶段的患者比例有所增加。治疗方面没有发生重大变化。在研究期间,疾病范围、年龄和性别对生存率产生了持续影响。诊断时患有局限性疾病的黑色素瘤患者的预期生存率远高于患有播散性疾病的患者。诊断时的年龄对后续生存率有明显影响,年轻患者的预后比老年患者更好。在所有年龄组中,女性的相对生存率高于男性。