Pace-Asciak C R, Rangaraj G
Biochim Biophys Acta. 1977 Mar 25;486(3):583-5. doi: 10.1016/0005-2760(77)90113-8.
Homogenates of the lamb ductus arteriosus at term have the capacity to convert exogenous arachidonic acid into prostaglandins E2, F2alpha and 6-ketoprostaglandin F1alpha. No evidence was obtained for the formation of prostaglandin D2 and thromboxane B2. All products were quantitated by mass spectrometry. 6-Ketoprostaglandin F1alpha was the major compound, formed in amounts in excess of 10 fold over prostalgandins E2 and F2alpha.
足月羔羊动脉导管的匀浆具有将外源性花生四烯酸转化为前列腺素E2、F2α和6-酮前列腺素F1α的能力。未获得前列腺素D2和血栓素B2形成的证据。所有产物均通过质谱法定量。6-酮前列腺素F1α是主要化合物，其生成量比前列腺素E2和F2α高出10倍以上。
