几种大鼠组织中前列腺素生物合成途径的分布。6-酮前列腺素F1α的形成。
Distribution of prostaglandin biosynthetic pathways in several rat tissues. Formation of 6-ketoprostaglandin F1alpha.
作者信息
Pace-Asciak C R, Rangaraj G
出版信息
Biochim Biophys Acta. 1977 Mar 25;486(3):579-82. doi: 10.1016/0005-2760(77)90112-6.
PMID:856290
Abstract
The capacity of homogenates of rat lung, liver, spleen, whole stomach, stomach fundus, kidney and heart to form prostaglandin E2, F2alpha, D2, thromboxane B2 and 6-ketoprostaglandin F1alpha was investigated. All products were quantitated by mass spectrometry. The results demonstrated interesting differences between tissues in the direction of the 'prostaglandin synthetase' to specific products (e.g. as in spleen and stomach).
摘要
研究了大鼠肺、肝、脾、全胃、胃底、肾和心脏匀浆形成前列腺素E2、F2α、D2、血栓素B2和6-酮前列腺素F1α的能力。所有产物均通过质谱法定量。结果表明，不同组织在“前列腺素合成酶”向特定产物的转化方向上存在有趣的差异（例如在脾脏和胃中）。
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