Pettit G H, Sauerbrey R, Tittel F K, Weilbacher D, Henry P D
FDA Center for Devices and Radiological Health, Rockville, Maryland 20857.
Lasers Surg Med. 1993;13(3):279-83. doi: 10.1002/lsm.1900130304.
The temporal modification of XeCl laser pulses reflected from human aorta tissue immersed in saline has been studied. Dynamic tissue reflectivity of both normal and atherosclerotic tissues has been examined for various incident pulse fluences between 0.7 and 6.5 J/cm2. Changes in reflected pulse duration are observed for fluences at or above 2.6 J/cm2 with normal tissue targets and 3.0 J/cm2 with calcified plaque. Such reflected pulse analysis may prove useful in identifying tissue targets for ablation during laser angioplasty.
研究了从浸泡在盐水中的人体主动脉组织反射的XeCl激光脉冲的时间变化。对于0.7至6.5 J/cm²之间的各种入射脉冲能量密度，检测了正常组织和动脉粥样硬化组织的动态组织反射率。当正常组织靶的能量密度达到或高于2.6 J/cm²以及钙化斑块的能量密度达到3.0 J/cm²时，观察到反射脉冲持续时间的变化。这种反射脉冲分析可能被证明在激光血管成形术期间识别消融的组织靶点方面是有用的。
