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极大螺旋藻对富含果糖饮食诱导大鼠脂肪肝的预防作用:初步报告

Preventive effect of Spirulina maxima on the fatty liver induced by a fructose-rich diet in the rat, a preliminary report.

作者信息

González de Rivera C, Miranda-Zamora R, Díaz-Zagoya J C, Juárez-Oropeza M A

机构信息

Departamento de Bioquímica, Facultad de Medicina, UNAM, México, D.F.

出版信息

Life Sci. 1993;53(1):57-61. doi: 10.1016/0024-3205(93)90611-6.

DOI:10.1016/0024-3205(93)90611-6
PMID:8515682
Abstract

Cyanobacteria Spirulina maxima from Texcoco Lake in Mexico was administered as a 5% component of a purified diet, to Wistar rats together with a high percentage of fructose (60%) and its effect on several lipid fractions of plasma and liver was studied and compared to those of rats fed purified diets containing 60% of glucose or 60% of fructose. A preventive effect of Spirulina maxima on the fructose-induced increase of the liver triglycerides level was observed together with an elevation of the phospholipid concentration in this tissue. On the other hand Spirulina maxima produced a plasma cholesterol level even lower than that observed in the control group.

摘要

将来自墨西哥特斯科科湖的蓝藻极大螺旋藻作为纯化日粮5%的成分,与高比例的果糖(60%)一起喂给Wistar大鼠,研究其对血浆和肝脏中几种脂质组分的影响,并与喂食含60%葡萄糖或60%果糖的纯化日粮的大鼠进行比较。观察到极大螺旋藻对果糖诱导的肝脏甘油三酯水平升高有预防作用,同时该组织中的磷脂浓度有所升高。另一方面,极大螺旋藻使血浆胆固醇水平甚至低于对照组。

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