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大脑皮质中过度活跃决定因素结构在癫痫发作活动功能复合体形成中的作用。

Role of hyperactive determinant structures in the creation of functional complexes of seizure activity in the cerebral cortex.

作者信息

Kryzhanovskii G N, Makul'kin R F, Shandra A A

出版信息

Neurosci Behav Physiol. 1979 Oct-Dec;9(4):401-5. doi: 10.1007/BF01185065.

DOI:10.1007/BF01185065
PMID:492510
Abstract

Foci of enhanced excitability, with independent discharge patterns, were created by subconvulsive strychninization in experiments on cats. A focus of more powerful excitation created with the same strychnine played the role of determinant despatch station (DDS). Its importance is that it determines the character of activity of the other foci of excitation, strengthens excitation in them, combines them into a single functional complex, and determines the character of activity of the whole complex. This complex can be destroyed by suppressing the DDS with pentobarbital. Blocking individual destination stations included in the complex does not lead to its destruction.

摘要

在猫的实验中,通过亚惊厥剂量的马钱子碱处理产生了具有独立放电模式的兴奋性增强灶。用相同剂量马钱子碱产生的更强兴奋灶起到了决定性发送站(DDS)的作用。其重要性在于它决定了其他兴奋灶的活动特征,增强了它们的兴奋,将它们组合成一个单一的功能复合体,并决定了整个复合体的活动特征。用戊巴比妥抑制决定性发送站可破坏这个复合体。阻断复合体中包含的各个目的站不会导致其破坏。

相似文献

1
Role of hyperactive determinant structures in the creation of functional complexes of seizure activity in the cerebral cortex.大脑皮质中过度活跃决定因素结构在癫痫发作活动功能复合体形成中的作用。
Neurosci Behav Physiol. 1979 Oct-Dec;9(4):401-5. doi: 10.1007/BF01185065.
2
[Role of hyperactive determinant structures in the creation of functional complexes of seizure activity in the cerebral cortex].[大脑皮质中癫痫活动功能复合体形成过程中过度活跃决定结构的作用]
Biull Eksp Biol Med. 1977 Jan;83(1):5-10.
3
[Formation of determinant structures and functional complexes in the neocortex when the brain is transected at different levels].[当大脑在不同水平横断时新皮质中决定性结构和功能复合体的形成]
Fiziol Zh SSSR Im I M Sechenova. 1980 Jun;66(6):791-801.
4
[Functional interaction between the determinant and other foci of epileptiform activity created in the cortex of both cerebral hemispheres].[大脑两半球皮质中产生的癫痫样活动的决定因素与其他病灶之间的功能相互作用]
Biull Eksp Biol Med. 1978 Aug;86(8):142-6.
5
[Formation of epileptic activity complexes in the cerebral cortex as a result of a determinant focus induced by acetylcholine].[乙酰胆碱诱导的决定性病灶导致大脑皮质癫痫活动复合体的形成]
Biull Eksp Biol Med. 1979 Feb;87(2):117-21.
6
[Modeling of determinant and dependent foci of epileptic activity in the rat cerebral cortex].[大鼠大脑皮层癫痫活动的决定性病灶和依赖性病灶建模]
Biull Eksp Biol Med. 1979 Mar;87(3):217-20.
7
[Mechanism of formation of epileptic activity complexes in the cerebral cortex under the influence of a determinant focus].[在决定性病灶影响下大脑皮质癫痫活动复合体的形成机制]
Biull Eksp Biol Med. 1978;86(7):14-9.
8
[Effect of determinant on formation of the complexes of hyperactivity foci in rabbit cerebral cortex].[决定因素对兔大脑皮层多动病灶复合物形成的影响]
Biull Eksp Biol Med. 1982 Oct;94(10):13-5.
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[Principle of the determinant and formation of complexes of epileptic activity].[癫痫活动复合体的决定因素及形成原理]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(4):547-56.
10
[Formation of epileptic activity complexes under the effect of the determinant focus in the cortex isolé].[孤立皮层中决定性病灶作用下癫痫活动复合体的形成]
Biull Eksp Biol Med. 1979 Oct;88(10):408-12.

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Clinical symptoms and performance on the Continuous Performance Test in children with attention deficit hyperactivity disorder between subtypes: a natural follow-up study for 6 months.注意缺陷多动障碍亚类儿童的临床症状和连续性能测试表现:6 个月自然随访研究。
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本文引用的文献

1
The problem of the frontal lobe: a reinterpretation.额叶问题:一种重新诠释
J Psychiatr Res. 1971 Aug;8(3):167-87. doi: 10.1016/0022-3956(71)90017-3.
2
[A "dispatch station" phenomenon in the central nervous system pathology].[中枢神经系统病理学中的一种“调度站”现象]
Patol Fiziol Eksp Ter. 1973 Jul-Aug;17(4):3-10.
3
[Study of the pain syndrome of spinal origin (the concept of a generative mechanism for the pain syndrome)].[脊柱源性疼痛综合征的研究(疼痛综合征的发生机制概念)]
Biull Eksp Biol Med. 1974 Jul;78(7):15-20.
4
Cortico-cortical connections in the rhesus monkey.恒河猴的皮质-皮质连接
Brain Res. 1969 Mar;13(1):13-36. doi: 10.1016/0006-8993(69)90141-3.
5
"Generalized" epileptic seizures elicited by electrical stimulation of the frontal lobe in man.通过对人类额叶进行电刺激引发的“全身性”癫痫发作。
Electroencephalogr Clin Neurophysiol. 1974 Sep;37(3):275-82. doi: 10.1016/0013-4694(74)90031-5.
6
[Experimental vestibulopathy produced as a result of formation of a generator of pathologically enhanced excitation in the vestibular nuclei (phenomenon of a determinative dispatch station)].
Biull Eksp Biol Med. 1976 Feb;81(2):147-50.
7
[Cortico-cortical connections of the orbito-frontal cortex].[眶额皮质的皮质-皮质连接]
Fiziol Zh SSSR Im I M Sechenova. 1975 Nov;61(11):1597-1604.