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抑制前列腺素合成作为治疗胆绞痛的方法。

Inhibition of prostaglandin synthesis as a treatment for biliary pain.

作者信息

Thornell E, Jansson R, Kral J G, Svanvik J

出版信息

Lancet. 1979 Mar 17;1(8116):584. doi: 10.1016/s0140-6736(79)91009-2.

DOI:10.1016/s0140-6736(79)91009-2
PMID:85168
Abstract

Twenty patients with confirmed gallbladder disease were treated with intravenous indomethacin during 24 separate attacks of biliary pain. In all cases the pain was promptly relieved and there were no important side-effects. Indomethacin, and inhibitor of prostaglandin synthesis, may reduce intraluminal pressure in the gallbladder, and relieve pain.

摘要

20例确诊为胆囊疾病的患者在24次单独发作的胆绞痛期间接受了静脉注射吲哚美辛治疗。在所有病例中,疼痛迅速缓解,且无严重副作用。吲哚美辛作为一种前列腺素合成抑制剂,可能会降低胆囊内压并缓解疼痛。

相似文献

1
Inhibition of prostaglandin synthesis as a treatment for biliary pain.抑制前列腺素合成作为治疗胆绞痛的方法。
Lancet. 1979 Mar 17;1(8116):584. doi: 10.1016/s0140-6736(79)91009-2.
2
Indomethacin intravenously--a new way for effective relief of biliary pain: a double-blind study in man.静脉注射消炎痛——有效缓解胆绞痛的新方法:人体双盲研究
Surgery. 1981 Sep;90(3):468-72.
3
Indomethacin by intravenous infusion in ureteral colic. A multicentre study.静脉输注吲哚美辛治疗输尿管绞痛。一项多中心研究。
Scand J Urol Nephrol. 1982;16(3):221-5. doi: 10.3109/00365598209179757.
4
[Indomethacin in the treatment of acute cholecystitis and biliary colic].[吲哚美辛治疗急性胆囊炎和胆绞痛]
G E N. 1991 Jan-Mar;45(1):32-7.
5
Biliary colic treatment and acute cholecystitis prevention by prostaglandin inhibitor.
Dig Dis Sci. 1989 Jun;34(6):809-11. doi: 10.1007/BF01540262.
6
[Echographic and ERCP-manometric study of gallbladder and Oddi's sphincter behavior in biliary colic in patients with cholelithiasis. Effects of cerulein].
Minerva Chir. 1996 Dec;51(12):1145-9.
7
Mechanisms in the development of acute cholecystitis and biliary pain. A study on the role of prostaglandins and effects of indomethacin.
Scand J Gastroenterol Suppl. 1982;76:1-31.
8
Double-blind evaluation of intravenous indomethacin and oxycone-papaverine in the treatment of acute biliary pain.
Acta Chir Scand. 1985;151(6):561-4.
9
Administration of rectal indomethacin does not reduce the requirement for intravenous narcotic analgesia in acute renal colic.直肠给予吲哚美辛并不能降低急性肾绞痛患者对静脉注射麻醉性镇痛药的需求。
Eur J Emerg Med. 1996 Jun;3(2):92-4. doi: 10.1097/00063110-199606000-00006.
10
Treatment of ureteric colic. Intravenous versus rectal administration of indomethacin.输尿管绞痛的治疗。吲哚美辛静脉注射与直肠给药对比
Br J Urol. 1990 Jun;65(6):576-9. doi: 10.1111/j.1464-410x.1990.tb14823.x.

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Non-steroid anti-inflammatory drugs for biliary colic.用于胆绞痛的非甾体抗炎药。
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Diclofenac sodium in biliary colic: a double blind trial.双氯芬酸钠治疗胆绞痛:一项双盲试验
Br Med J (Clin Res Ed). 1984 Apr 7;288(6423):1042. doi: 10.1136/bmj.288.6423.1042.
4
Pharmacokinetics of tolfenamic acid: disposition in bile, blood and urine after intravenous administration to man.托芬那酸的药代动力学:静脉注射给人后在胆汁、血液和尿液中的处置情况。
Eur J Clin Pharmacol. 1984;27(3):349-54. doi: 10.1007/BF00542174.
5
Pain--mechanics and management.疼痛——力学原理与管理
West J Med. 1984 Sep;141(3):347-57.