老年人的胰多肽与胰腺外分泌功能
Pancreatic polypeptide and exocrine pancreatic function in the elderly.
作者信息
al-Modaris F I, Taylor I C, McConnell J G, Power M J, Armstrong E, Buchanan K D
机构信息
Department of Health Care for the Elderly, Ulster Hospital, Dundonald, Belfast.
出版信息
Ulster Med J. 1993 Apr;62(1):44-9.
The relationship between exocrine pancreatic function and plasma pancreatic polypeptide levels was studied in 14 normal elderly subjects and in ten elderly patients with exocrine pancreatic insufficiency determined by the para-amino-benzoic acid test. There was a decrease in the total pancreatic polypeptide response after a standard mixed meal in the group with pancreatic insufficiency (t = 2.753, p = 0.01). An increase above basal of less than 100% in plasma pancreatic polypeptide levels 30 min after a standard mixed meal is strongly associated with exocrine pancreatic insufficiency (Fisher's exact test, p = 0.005).
在14名正常老年人和10名经对氨基苯甲酸试验确定为外分泌性胰腺功能不全的老年患者中，研究了外分泌性胰腺功能与血浆胰多肽水平之间的关系。胰腺功能不全组在标准混合餐后，总的胰多肽反应有所下降（t = 2.753，p = 0.01）。标准混合餐后30分钟，血浆胰多肽水平较基础值升高不足100%与外分泌性胰腺功能不全密切相关（费舍尔精确检验，p = 0.005）。
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