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100例酒精性肝病患者的性别差异

Sex-related differences among 100 patients with alcoholic liver disease.

作者信息

Morgan M Y, Sherlock S

出版信息

Br Med J. 1977 Apr 9;1(6066):939-41. doi: 10.1136/bmj.1.6066.939.

DOI:10.1136/bmj.1.6066.939
PMID:851792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1605784/
Abstract

During 1975 we studied 100 patients--77 men and 23 women--who had a history of alcohol abuse and disturbed liver function test results. On presentation the women were less likely to be suspected of alcohol abuse (9; 38%) than the men (59; 77%). Although the quantity of alcohol consumed and length of history of alcohol abuse were similar for men and women, the incidence of chronic advanced liver disease was higher among women (86%) than among men (65%). Women, however, were less likely to have developed primary liver cell cancer. Overall the women had a higher incidence of other alcohol-related disorders and were less likely to stop abusing alcohol (2; 9%) than were their male counterparts (22; 29%). Women seem to be more susceptible to alcohol-related disease.

摘要

1975年期间,我们研究了100名有酗酒史且肝功能检查结果异常的患者,其中77名男性,23名女性。就诊时,女性比男性更不容易被怀疑有酗酒问题(女性9例,占38%;男性59例,占77%)。尽管男性和女性的饮酒量及酗酒史长度相似,但女性慢性晚期肝病的发病率(86%)高于男性(65%)。然而,女性患原发性肝细胞癌的可能性较小。总体而言,女性其他酒精相关疾病的发病率较高,且与男性相比,她们戒酒的可能性较小(女性2例,占9%;男性22例,占29%)。女性似乎更容易患酒精相关疾病。

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本文引用的文献

1
Physical disease in alcoholism. Initial survey of 1,000 patients.酒精中毒中的身体疾病。对1000名患者的初步调查。
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Epidemiology of alcoholic cirrhosis.酒精性肝硬化的流行病学
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Studies in alcoholic liver disease in Britain. I. Clinical and pathological patterns related to natural history.英国酒精性肝病研究。I. 与自然史相关的临床和病理模式
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Cirrhosis and hepatoma in alcoholics.酗酒者的肝硬化与肝癌
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