Marchant B, Ranjadayalan K, Stevenson R, Wilkinson P, Timmis A D
Department of Cardiology, London Chest Hospital, London.
Br Heart J. 1993 May;69(5):385-7. doi: 10.1136/hrt.69.5.385.
To determine the circadian and seasonal variations in the incidence of acute myocardial infarction and the influence of environmental temperature.
633 consecutive patients with acute myocardial infarction admitted to a coronary care unit over four years.
Coronary care unit in a district general hospital.
An observational study.
The onset of acute myocardial infarction had a circadian rhythm with a peak in the second quarter of the day. A seasonal variation was also found with a significant winter peak. There was, however, an excess of infarctions on colder days in both winter and summer indicating that the effect of environmental temperature on the onset of acute myocardial infarction is independent of the time of year.
Acute myocardial infarction is more common in winter and more common on colder days, independent of season. Environmental temperature may play an important part in the pathogenesis of acute myocardial infarction.
确定急性心肌梗死发病率的昼夜及季节变化以及环境温度的影响。
连续四年入住冠心病监护病房的633例急性心肌梗死患者。
地区综合医院的冠心病监护病房。
一项观察性研究。
急性心肌梗死的发病具有昼夜节律，在一天中的第二个时间段达到高峰。还发现了季节性变化，冬季有一个显著的高峰。然而，在冬季和夏季，寒冷的日子里梗死发生率都过高，这表明环境温度对急性心肌梗死发病的影响与一年中的时间无关。
急性心肌梗死在冬季更常见，在寒冷的日子里更常见，与季节无关。环境温度可能在急性心肌梗死的发病机制中起重要作用。
