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氯喹引起的限制性心肌病。

Restrictive cardiomyopathy caused by chloroquine.

作者信息

Iglesias Cubero G, Rodriguez Reguero J J, Rojo Ortega J M

机构信息

Department of Cardiology, Hospital Central de Asturias, University of Oviedo, Spain.

出版信息

Br Heart J. 1993 May;69(5):451-2. doi: 10.1136/hrt.69.5.451.

Abstract

A 59 year old white woman who had been treated with chloroquine phosphate for 25 years presented with signs of congestive heart failure and was diagnosed as having restrictive cardiomyopathy by non-invasive methods. Electron microscopy of a biopsy specimen of skeletal muscle showed lesions compatible with chloroquine myopathy. The patient died five weeks after presentation. Electron microscopy of heart tissue showed similar lesions to those of the skeletal muscle.

摘要

一名59岁的白人女性,使用磷酸氯喹治疗25年,出现充血性心力衰竭症状,通过非侵入性方法被诊断为限制性心肌病。骨骼肌活检标本的电子显微镜检查显示有与氯喹肌病相符的病变。患者在出现症状五周后死亡。心脏组织的电子显微镜检查显示出与骨骼肌相似的病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4f/1025112/7d6035141513/brheartj00015-0083-a.jpg

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