Cacciapuoti B, Ciceroni L, Fontana L, Perricone R
Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanità, Rome, Italy.
Zentralbl Bakteriol. 1993 Feb;278(1):102-11. doi: 10.1016/s0934-8840(11)80283-5.
A report is presented about the capability of complement to directly clump Borrelia burgdorferi. The new phenomenon which has been termed "microbial adherence", is either antibody-independent or requires the presence of "sensitizing" antibodies depending the strains tested. Microbial adherence is associated with immobilization and killing of borrelias. A microbial adherence immobilization assay for B. burgdorferi (MAIA-BB) was developed to detect sensitizing antibodies in patients with Lyme borreliosis and in B. burgdorferi-infected animals.
本文报道了补体直接凝集伯氏疏螺旋体的能力。这种被称为“微生物黏附”的新现象，要么不依赖抗体，要么根据所测试的菌株需要“致敏”抗体的存在。微生物黏附与伯氏疏螺旋体的固定和杀伤有关。为检测莱姆病患者和感染伯氏疏螺旋体的动物体内的致敏抗体，开发了一种针对伯氏疏螺旋体的微生物黏附固定试验（MAIA-BB）。
