Hampson D J, Woodward J M, Connaughton I D
School of Veterinary Studies, Murdoch University, Perth, Western Australia.
Epidemiol Infect. 1993 Jun;110(3):575-81. doi: 10.1017/s0950268800050998.
A total of 79 Australian isolates of beta-haemolytic Escherichia coli from cases of porcine postweaning diarrhoea (PWD), and 18 isolates of serotype O 149:K91:K88 (F4) from unweaned pigs from Australia, Indonesia and Denmark, were examined by multilocus enzyme electrophoresis. These were divided into 57 electrophoretic types (ETs), with an overall mean genetic diversity per enzyme locus of 0.466. This value closely resembled that previously recorded for the whole species. Not only was the collection diverse, but there was considerable genetic heterogeneity amongst PWD isolates of the same serogroup. Isolates from serogroups O 8 and O 138 were most varied, whilst many from serogroups O 141 and O 149 were more closely related. In contrast, the isolates from the unweaned pigs all belonged to only one ET.
对来自猪断奶后腹泻(PWD)病例的79株澳大利亚β-溶血大肠杆菌分离株,以及来自澳大利亚、印度尼西亚和丹麦的未断奶仔猪的18株O 149:K91:K88(F4)血清型分离株进行了多位点酶电泳分析。这些分离株被分为57种电泳类型(ETs),每个酶位点的总体平均遗传多样性为0.466。该值与之前记录的整个物种的值非常相似。不仅该集合具有多样性,而且同一血清群的PWD分离株之间存在相当大的遗传异质性。来自O 8和O 138血清群的分离株差异最大,而来自O 141和O 149血清群的许多分离株关系更为密切。相比之下,来自未断奶仔猪的分离株都只属于一个ET。