Kolesov V G, Efimov S N, Perminov N Kh
Med Tr Prom Ekol. 1995(8):35-8.
The follow-up studies of patients with vibration disease caused by local vibration proved diagnostic value of minor skin response of dorsal hand surface and anterior surface of arm or forearm, if subjected to irritation with mixture of chloroform and ethanol. Depressed skin receptors during the disease are diagnosed through longer latent period of burning sensation in two of three points irritated on skin of the upper limb. The diagnostic method based on chemical stimulation of skin receptors is highly sensitive (86.9%) and specific (94.4%), especially for early stages of the disease, promoting detection of subclinical peripheral neuropathy caused by vibration. Due to its simplicity and availability the method could replace algesimetry in mass screening among workers exposed to vibration.
对局部振动所致振动病患者的随访研究证明，如果用氯仿和乙醇混合物刺激，手背表面以及手臂或前臂前表面的轻微皮肤反应具有诊断价值。该病患者的皮肤感受器功能减退可通过在上肢皮肤受刺激的三个点中有两个点的灼痛潜伏期延长来诊断。基于对皮肤感受器进行化学刺激的诊断方法具有高度敏感性（86.9%）和特异性（94.4%），尤其对于疾病早期，有助于检测出由振动引起的亚临床周围神经病变。由于该方法简单易行且可操作性强，在对接触振动的工人进行大规模筛查时可替代痛觉测量法。
