Rosenstein D L, Ryschon T W, Niemela J E, Elin R J, Balaban R S, Rubinow D R
Section on Behavioral Endocrinology, National Institute of Mental Health, Bethesda, MD 20892-1276, USA.
J Am Coll Nutr. 1995 Oct;14(5):486-90. doi: 10.1080/07315724.1995.10718540.
The hormonal regulation of magnesium (Mg) metabolism is poorly understood. Preliminary evidence suggests that reproductive hormones may influence Mg concentrations in various tissues. The purpose of this study was to determine if Mg concentrations in blood and muscle are affected by the phase of the menstrual cycle.
Magnesium measures were obtained from 16 women over the course of one complete menstrual cycle. The principal outcome measure was intracellular ionized Mg ([Mg++]i) in skeletal muscle as measured by 31P nuclear magnetic resonance spectroscopy. Three blood measures (serum, red blood cell, and mononuclear blood cell) of total Mg ([Mg]) were also obtained.
Mean Mg concentrations were stable across the menstrual cycle with no evidence of a menstrual cycle phase effect for any of the measures. Furthermore, skeletal muscle [Mg++]i was not correlated with any blood measure of [Mg].
These results suggest that physiologic fluctuations in reproductive hormones do not influence either blood [Mg] or skeletal muscle [Mg++]i in healthy, regularly cycling women.
镁（Mg）代谢的激素调节机制尚不清楚。初步证据表明，生殖激素可能会影响各种组织中的镁浓度。本研究的目的是确定血液和肌肉中的镁浓度是否受月经周期阶段的影响。
在一个完整的月经周期内，对16名女性进行了镁含量测量。主要观察指标是通过31P核磁共振波谱法测量的骨骼肌细胞内游离镁（[Mg++]i）。还获得了三种血液指标（血清、红细胞和单核血细胞）的总镁（[Mg]）含量。
整个月经周期内平均镁浓度稳定，所有测量指标均未显示出月经周期阶段效应。此外，骨骼肌[Mg++]i与任何血液[Mg]测量指标均无相关性。
这些结果表明，生殖激素的生理波动不会影响健康、月经周期规律女性的血液[Mg]或骨骼肌[Mg++]i。
