在急性感染马的血液单核细胞分化过程中，马传染性贫血病毒的复制上调。
Equine infectious anemia virus replication is upregulated during differentiation of blood monocytes from acutely infected horses.
作者信息
Sellon D C, Walker K M, Russell K E, Perry S T, Covington P, Fuller F J
机构信息
Department of Food Animal and Equine Medicine, North Carolina State University College of Veterinary Medicine, Raleigh 27606, USA.
出版信息
J Virol. 1996 Jan;70(1):590-4. doi: 10.1128/JVI.70.1.590-594.1996.
Abstract
Equine infectious anemia virus is a lentivirus that replicates in mature tissue macrophages of horses. Ponies were infected with equine infectious anemia virus. During febrile episodes, proviral DNA was detectable, but viral mRNA was not detectable. As cultured blood monocytes from these ponies differentiated into macrophages, viral expression was upregulated. In situ hybridization confirmed that viral transcription occurred in mature macrophages.
摘要
马传染性贫血病毒是一种慢病毒，在马的成熟组织巨噬细胞中复制。小马感染了马传染性贫血病毒。在发热期可检测到前病毒DNA，但未检测到病毒mRNA。随着这些小马培养的血液单核细胞分化为巨噬细胞，病毒表达上调。原位杂交证实病毒转录发生在成熟巨噬细胞中。
相似文献
1
Equine infectious anemia virus replication is upregulated during differentiation of blood monocytes from acutely infected horses.在急性感染马的血液单核细胞分化过程中，马传染性贫血病毒的复制上调。
J Virol. 1996 Jan;70(1):590-4. doi: 10.1128/JVI.70.1.590-594.1996.
2
Wild-type equine infectious anemia virus replicates in vivo predominantly in tissue macrophages, not in peripheral blood monocytes.野生型马传染性贫血病毒在体内主要在组织巨噬细胞中复制，而不在外周血单核细胞中复制。
J Virol. 1992 Oct;66(10):5906-13. doi: 10.1128/JVI.66.10.5906-5913.1992.
3
Tissue sites of persistent infection and active replication of equine infectious anemia virus during acute disease and asymptomatic infection in experimentally infected equids.实验感染马属动物在急性疾病和无症状感染期间马传染性贫血病毒持续感染和活跃复制的组织部位。
J Virol. 2000 Apr;74(7):3112-21. doi: 10.1128/jvi.74.7.3112-3121.2000.
4
Equine infectious anemia virus is found in tissue macrophages during subclinical infection.马传染性贫血病毒在亚临床感染期间存在于组织巨噬细胞中。
J Virol. 1998 Sep;72(9):7263-9. doi: 10.1128/JVI.72.9.7263-7269.1998.
5
Phorbol ester stimulation of equine macrophage cultures alters expression of equine infectious anemia virus.佛波酯刺激马巨噬细胞培养物会改变马传染性贫血病毒的表达。
Vet Microbiol. 1996 Oct;52(3-4):209-21. doi: 10.1016/s0378-1135(96)00071-5.
6
Equine endothelial cells support productive infection of equine infectious anemia virus.马内皮细胞支持马传染性贫血病毒的有效感染。
J Virol. 1998 Nov;72(11):9291-7. doi: 10.1128/JVI.72.11.9291-9297.1998.
7
Immune responses and viral replication in long-term inapparent carrier ponies inoculated with equine infectious anemia virus.接种马传染性贫血病毒的长期隐性携带小马的免疫反应和病毒复制
J Virol. 2000 Jul;74(13):5968-81. doi: 10.1128/jvi.74.13.5968-5981.2000.
8
Proviral sequences detected by polymerase chain reaction in peripheral blood cells of horses with equine infectious anemia lentivirus.
Arch Virol. 1991;117(1-2):109-19. doi: 10.1007/BF01310496.
9
Monocyte maturation controls expression of equine infectious anemia virus.单核细胞成熟控制马传染性贫血病毒的表达。
J Virol. 1994 Oct;68(10):6270-9. doi: 10.1128/JVI.68.10.6270-6279.1994.
10
Replication in vitro and in vivo of an equine infectious anemia virus mutant deficient in dUTPase activity.缺乏dUTPase活性的马传染性贫血病毒突变体在体外和体内的复制
J Virol. 1995 May;69(5):2881-8. doi: 10.1128/JVI.69.5.2881-2888.1995.
引用本文的文献
1
Equine Infectious Anemia Virus Cellular Partners Along the Viral Cycle.马传染性贫血病毒在病毒周期中的细胞伴侣
Viruses. 2024 Dec 24;17(1):5. doi: 10.3390/v17010005.
2
EIAV S2 enhances pro-inflammatory cytokine and chemokine response in infected macrophages.EIAV S2 增强感染巨噬细胞中促炎细胞因子和趋化因子的反应。
Virology. 2010 Feb 5;397(1):217-23. doi: 10.1016/j.virol.2009.11.005. Epub 2009 Nov 28.
3
Characterization of a new 5' splice site within the caprine arthritis encephalitis virus genome: evidence for a novel auxiliary protein.山羊关节炎脑炎病毒基因组内一个新的5'剪接位点的特征分析：一种新型辅助蛋白的证据
Retrovirology. 2008 Feb 29;5:22. doi: 10.1186/1742-4690-5-22.
4
Assessment of Equine Autoimmune Thrombocytopenia (EAT) by flow cytometry.通过流式细胞术评估马自身免疫性血小板减少症（EAT）。
BMC Blood Disord. 2001;1(1):1. doi: 10.1186/1471-2326-1-1.
5
Tissue sites of persistent infection and active replication of equine infectious anemia virus during acute disease and asymptomatic infection in experimentally infected equids.实验感染马属动物在急性疾病和无症状感染期间马传染性贫血病毒持续感染和活跃复制的组织部位。
J Virol. 2000 Apr;74(7):3112-21. doi: 10.1128/jvi.74.7.3112-3121.2000.
6
The S2 gene of equine infectious anemia virus is a highly conserved determinant of viral replication and virulence properties in experimentally infected ponies.马传染性贫血病毒的S2基因是实验感染小马中病毒复制和毒力特性的高度保守决定因素。
J Virol. 2000 Jan;74(1):573-9. doi: 10.1128/jvi.74.1.573-579.2000.
7
The S2 gene of equine infectious anemia virus is dispensable for viral replication in vitro.马传染性贫血病毒的S2基因在体外病毒复制中并非必需。
J Virol. 1998 Oct;72(10):8344-8. doi: 10.1128/JVI.72.10.8344-8348.1998.
8
Equine infectious anemia virus is found in tissue macrophages during subclinical infection.马传染性贫血病毒在亚临床感染期间存在于组织巨噬细胞中。
J Virol. 1998 Sep;72(9):7263-9. doi: 10.1128/JVI.72.9.7263-7269.1998.
本文引用的文献
1
Pathogenesis of human immunodeficiency virus infection.人类免疫缺陷病毒感染的发病机制
Microbiol Rev. 1993 Mar;57(1):183-289. doi: 10.1128/mr.57.1.183-289.1993.
2
Production and characterization of a monoclonal antibody recognizing a cytoplasmic antigen of equine mononuclear phagocytes.一种识别马单核吞噬细胞胞质抗原的单克隆抗体的制备与鉴定
Vet Immunol Immunopathol. 1993 May;36(4):303-18. doi: 10.1016/0165-2427(93)90027-2.
3
Monocyte maturation controls expression of equine infectious anemia virus.单核细胞成熟控制马传染性贫血病毒的表达。
J Virol. 1994 Oct;68(10):6270-9. doi: 10.1128/JVI.68.10.6270-6279.1994.
4
The immunopathogenesis of equine infectious anemia virus.马传染性贫血病毒的免疫发病机制。
Virus Res. 1994 May;32(2):111-38. doi: 10.1016/0168-1702(94)90038-8.
5
Release of human immunodeficiency virus by THP-1 cells and human macrophages is regulated by cellular adherence and activation.THP-1细胞和人类巨噬细胞释放人类免疫缺陷病毒受细胞黏附和激活的调节。
J Virol. 1993 Jun;67(6):3569-75. doi: 10.1128/JVI.67.6.3569-3575.1993.
6
Activation of caprine arthritis-encephalitis virus expression during maturation of monocytes to macrophages.单核细胞成熟为巨噬细胞过程中山羊关节炎-脑炎病毒表达的激活。
Infect Immun. 1983 Jul;41(1):67-73. doi: 10.1128/iai.41.1.67-73.1983.
7
Antigenic variation during persistent infection by equine infectious anemia virus, a retrovirus.马传染性贫血病毒（一种逆转录病毒）持续感染期间的抗原变异
J Biol Chem. 1984 Aug 25;259(16):10539-44.
8
Excretion of equine infectious anemia virus from horses infected with the virus.感染马传染性贫血病毒的马匹对该病毒的排泄情况。
Natl Inst Anim Health Q (Tokyo). 1973 Winter;13(4):182-6.
9
Viremia and immunological responses in horses infected with equine infectious anemia virus.感染马传染性贫血病毒的马匹的病毒血症和免疫反应。
Natl Inst Anim Health Q (Tokyo). 1969 Spring;9(1):1-9.
10
Tropism of sheep lentiviruses for monocytes: susceptibility to infection and virus gene expression increase during maturation of monocytes to macrophages.绵羊慢病毒对单核细胞的嗜性：单核细胞成熟为巨噬细胞过程中感染易感性及病毒基因表达增加。
J Virol. 1986 Apr;58(1):67-74. doi: 10.1128/JVI.58.1.67-74.1986.
Zotero 插件