Büsen W, Peters J H, Hausen P
Eur J Biochem. 1977 Mar 15;74(1):203-8. doi: 10.1111/j.1432-1033.1977.tb11382.x.
Several enzymes with ribonuclease H specificity have been identified in bovine lymphoid tissue. Their nomenclature and some of their properties have been reported previously. In this study the time course of the induction of the different ribonuclease H activities during the stimulation of resting bovine lymph-node cells with concanavalin A was investigated. The activity of one of these enzymes (ribonuclease H IIb) increases in parallel with the induction of uridine incorporation and is well separated from the induction of ribonuclease H I, which increases together with DNA synthesis. These data indicate that the different ribonuclease H activities serve different physiological functions. They suggest that ribonuclease H I belongs to the set of enzymes which are involved in DNA synthesis.
在牛淋巴组织中已鉴定出几种具有核糖核酸酶H特异性的酶。它们的命名及其一些特性先前已有报道。在本研究中，研究了用伴刀豆球蛋白A刺激静止的牛淋巴结细胞期间不同核糖核酸酶H活性的诱导时间进程。其中一种酶（核糖核酸酶H IIb）的活性与尿苷掺入的诱导平行增加，并且与核糖核酸酶H I的诱导明显分开，核糖核酸酶H I与DNA合成一起增加。这些数据表明不同的核糖核酸酶H活性具有不同的生理功能。它们表明核糖核酸酶H I属于参与DNA合成的酶类。
