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Ultrastructural co-localisation of vimentin and cytokeratin in visceral glomerular epithelial cells of dogs with glomerulonephritis.

作者信息

Vilafranca M, Ferrer L, Wohlsein P, Trautwein G, Sanchez J, Navarro J A

机构信息

Unidad de Histología y Anatomía Patológica, Facultad de Veterinaria, Universidad Autónoma de Barcelona, Spain.

出版信息

Res Vet Sci. 1995 Jul;59(1):87-91. doi: 10.1016/0034-5288(95)90037-3.

DOI:10.1016/0034-5288(95)90037-3
PMID:8525093
Abstract

The expression of cytokeratin and vimentin was studied in the glomerular epithelial cells of canine kidneys with and without glomerular abnormalities. Using ultrastructural, immunogold single and double labelling techniques, cytokeratin and vimentin were found together in the visceral glomerular epithelial cells (vGECs) of abnormal kidneys. In normal kidneys, the vGECs expressed only vimentin, and cytokeratin was found exclusively in parietal glomerular epithelial cells (pGECs). These results confirm previous findings in the same animals, obtained by immunohistological staining techniques.

摘要

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