Zaks A S, Bykova A A, Suslina M L
Farmakol Toksikol. 1977 Mar-Apr;40(2):190-3.
Experiments with rabbits showed the formation of antibodies in response to introduction of histamine-, serotonin-, kalllikrein-, bradykinin-proteinic conjugates. The influence of antibodies on the exudative reaction following introduction of histamine, serotonin, kallikrein, bradykinin, dextran and agar to rats was studied. The ability of antibodies to block both the introduced from outside specific mediators of inflammation and their natural analogues is demonstrated. This bears proof to the possibility of utilizing the specific antibodies in the study of the mediating structure common to various types of inflammation and for the regulation of the inflammatory process.
对兔子的实验表明，引入组胺、血清素、激肽释放酶、缓激肽 - 蛋白质结合物会引发抗体形成。研究了抗体对向大鼠引入组胺、血清素、激肽释放酶、缓激肽、右旋糖酐和琼脂后渗出反应的影响。证实了抗体能够阻断从外部引入的特定炎症介质及其天然类似物。这证明了利用特异性抗体研究各种炎症类型共有的介导结构以及调节炎症过程的可能性。
