Driscoll M D, Arnold J M, Sherebrin M H
Department of Medicine, University of Western Ontario, London.
Clin Invest Med. 1995 Oct;18(5):370-9.
Arterial pressure pulses are often measured noninvasively, but the influence of external recording forces has not been well documented. Accordingly, the main goal was to delineate pulse contour and amplitude distortion with progressively compressive forces applied to an external transducer. Ten young normal male subjects were studied while supine. Pulses were recorded at the end of a normal expiration over a range of forces (0.45-4.29, 0.42N increments) applied in a randomized order over first the brachial and then the radial artery. Pulse contours were Fourier analyzed and harmonic powers were normalized to the peak power at the fundamental frequency. Brachial artery pulse amplitudes progressively decreased (p = 0.013), whereas, those at the radial artery peaked at a recording force of 1.79 +/- 0.01N (p < 0.001) and subsequently decreased parallel to the brachial data with larger forces. No significant pulse contour distortions occurred at either the brachial or radial artery with applied forces of up to 2.18 +/- 0.02 and 2.59 +/- 0.02N, respectively, as indicated by the similarity of the relative power for harmonics 2-7. Radial artery pulses were distorted at and beyond a force of 2.99 +/- 0.01N as indicated by the increased relative power of harmonics 3-7 (p < 0.05). Therefore, despite significant alterations in pulse amplitude, the relative shape of pulses remains similar over a large range of lower recording forces.
动脉压脉搏通常采用无创测量，但外部记录力的影响尚未得到充分记录。因此，主要目的是通过对外部换能器逐渐施加压缩力来描绘脉搏轮廓和幅度失真。对10名年轻正常男性受试者进行了仰卧位研究。在正常呼气末，以随机顺序对肱动脉和桡动脉施加一系列力（0.45 - 4.29，增量为0.42N），记录脉搏。对脉搏轮廓进行傅里叶分析，并将谐波功率归一化为基频处的峰值功率。肱动脉脉搏幅度逐渐降低（p = 0.013），而桡动脉脉搏幅度在记录力为1.79±0.01N时达到峰值（p < 0.001），随后在更大的力作用下与肱动脉数据平行下降。分别施加高达2.18±0.02和2.59±0.02N的力时，肱动脉和桡动脉均未出现明显的脉搏轮廓失真，这由谐波2 - 7的相对功率相似性表明。当力达到2.99±0.01N及以上时，桡动脉脉搏出现失真，这由谐波3 - 7的相对功率增加表明（p < 0.05）。因此，尽管脉搏幅度有显著变化，但在较大范围的较低记录力下，脉搏的相对形状仍保持相似。
