Hornung W P, Holle R, Schulze Mönking H, Klingberg S, Buchkremer G
Klinik und Poliklinik für Psychiatrie, Universität Münster.
Nervenarzt. 1995 Nov;66(11):828-34.
In this study we look into the question of whether, in addition to neuroleptic treatment, relapse rates among schizophrenic patients can be reduced by means of a combined psychoeducational and psychotherapeutic intervention strategy for patients and their relatives. In a randomized controlled intervention study in an outpatient routine treatment setting, psychoeducational training for medication management, cognitive therapy and work with relatives' groups were compared with each other and with a control group. The patients continued their standard treatment, including neuroleptic relapse prevention. The study comprised 191 chronic DSM-III-R schizophrenics. Data were collected before and after an 8-month intervention phase and at the 1-year follow-up. The group receiving all three treatments had the lowest relapse rates. Moreover, numerous gains recorded in subjective findings suggest that therapeutic work with schizophrenic patients and their relatives is of clinically significant benefit.
在本研究中,我们探讨了一个问题:对于精神分裂症患者,除了使用抗精神病药物治疗外,是否可以通过对患者及其亲属采用心理教育与心理治疗相结合的干预策略来降低复发率。在一项门诊常规治疗环境下的随机对照干预研究中,将药物管理的心理教育培训、认知疗法以及亲属团体干预进行相互比较,并与一个对照组进行比较。患者继续接受包括预防抗精神病药物复发的标准治疗。该研究纳入了191名慢性DSM-III-R精神分裂症患者。在为期8个月的干预阶段前后以及1年随访时收集数据。接受所有三种治疗的组复发率最低。此外,主观结果中记录的众多改善表明,对精神分裂症患者及其亲属的治疗工作具有显著的临床益处。