McKnight J A, McCance D R, Lundy F T, Widsom G B, Hayes J R
Metabolic Unit, Western General Hospitals NHS Trust, Edinburgh.
Ulster Med J. 1995 Oct;64(2):157-63.
The role of alcohol in causing acute medical admissions is recognised but not well quantified. Using a questionnaire we have studied prospectively alcohol intake in patients aged 18-60 years admitted to a medical unit and have analysed the contribution of alcohol to their admission. One hundred and six patients (61 male: 45 female) who fulfilled our preset age criteria were studied. Alcohol intake (mean +/- SEM) was 9 +/- 1 and 12 +/- 1 units on average and heavy drinking days respectively, and 38 +/- 6 units during their last drinking week. Gamma glutamyl transferase (GGT) was > 60 U/l (upper limit of normal) in 29 (n = 92). Eighteen (30%) men had drunk > 50 units and seven (16%) women had taken > 35 units in their last drinking week. In 25 (41%) men and 11 (24%) women alcohol intake was felt to contribute to their admission. In this subgroup, intake was 15 +/- 2 and 20 +/- 1 units on average and heavy drinking days respectively, and 87 +/- 13 units in the last drinking week. GGT was available in 29 and was abnormal in 18. Admission diagnoses were drug overdose (n = 16), alcohol withdrawal symptoms (n = 7), liver disease (n = 6), haematemesis (n = 14) and others (n = 3). Fifteen (42%) felt they had a definite alcohol problem. The use and abuse of alcohol contributes significantly to the general medical workload in the age group studied.
酒精在导致急性入院治疗方面的作用已得到认可,但尚未得到很好的量化。我们通过问卷调查对入住内科病房的18至60岁患者的酒精摄入量进行了前瞻性研究,并分析了酒精对他们入院的影响。对106名符合我们预设年龄标准的患者(61名男性:45名女性)进行了研究。平均酒精摄入量(均值±标准误)在平时和重度饮酒日分别为9±1和12±1单位,在最后一个饮酒周为38±6单位。在92名患者中,29名患者的γ-谷氨酰转移酶(GGT)>60 U/l(正常上限)。在最后一个饮酒周,18名(30%)男性饮酒量>50单位,7名(16%)女性饮酒量>35单位。25名(41%)男性和11名(24%)女性的酒精摄入被认为与他们的入院有关。在这个亚组中,平均酒精摄入量在平时和重度饮酒日分别为15±2和20±1单位,在最后一个饮酒周为87±13单位。29名患者检测了GGT,其中18名异常。入院诊断为药物过量(n = 16)、酒精戒断症状(n = 7)、肝病(n = 6)、呕血(n = 14)和其他(n = 3)。15名(42%)患者认为自己有明确的酒精问题。在所研究的年龄组中,酒精的使用和滥用对内科总体工作量有显著影响。