Ndiweni N, Finch J M
AFRC Institute for Animal Health, Compton Laboratory, Newbury, UK.
Vet Immunol Immunopathol. 1995 Jul;47(1-2):111-21. doi: 10.1016/0165-2427(94)05382-3.
vitamin E and selenium have been observed to enhance the functions of bovine mammary gland macrophages and peripheral blood lymphocytes. In vitro supplementation with these compounds enhanced the production of neutrophil chemotaxins by macrophages stimulated with opsonised Staphylococcus aureus. Supplementation also enhanced the proliferation of peripheral blood lymphocytes in response to stimulation with concanavalin A but not to phytohaemagglutinin or pokeweed mitogen. There was no evidence of additive or synergistic effects of vitamin E and selenium. Results suggest that supplementation of cattle may optimise resistance to mastitis by enhancing the functions of resident macrophage and lymphocyte populations.
已观察到维生素E和硒可增强牛乳腺巨噬细胞和外周血淋巴细胞的功能。在体外补充这些化合物可增强经调理的金黄色葡萄球菌刺激的巨噬细胞产生中性粒细胞趋化因子的能力。补充还增强了外周血淋巴细胞在伴刀豆球蛋白A刺激下的增殖，但对植物血凝素或商陆有丝分裂原刺激无增强作用。没有证据表明维生素E和硒有相加或协同作用。结果表明，给牛补充这些物质可能通过增强驻留巨噬细胞和淋巴细胞群体的功能来优化对乳腺炎的抵抗力。
