Double isochromosome 8q as single cytogenetic aberration in acute myelo-monocytic leukemia.
作者信息
Vicari L, Sebastio L, Cirigliano V, Pugliese M T, Ferrara F
机构信息
Medical Genetics Service, Cardarelli Hospital, Naples, Italy.
出版信息
Leuk Lymphoma. 1995 Oct;19(3-4):351-3. doi: 10.3109/10428199509107909.
PMID:8535230
Abstract
We report a case of double isochromosome 8q as a single cytogenetic abnormality in a patient with acute myelo-monocytic leukemia. Similarly to rare cases with tetrasomy 8, the patient showed monocytic involvement and was refractory to cytotoxic chemotherapy. We conclude that this kind of cytogenetic aberration is probably associated with distinct morphologic and clinical characteristics.
摘要
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