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狭窄成形术治疗克罗恩病所致肠梗阻后的复发与再次手术:长期结果[已修正]

Recurrence and reoperation after strictureplasty for obstructive Crohn's disease: long-term results [corrected].

作者信息

Stebbing J F, Jewell D P, Kettlewell M G, Mortensen N J

机构信息

Department of Colorectal Surgery, John Radcliffe Hospital, Oxford, UK.

出版信息

Br J Surg. 1995 Nov;82(11):1471-4. doi: 10.1002/bjs.1800821108.

Abstract

Strictureplasty extends the surgical options for the treatment of obstructive Crohn's disease. Over 15 years, 52 patients had 241 strictureplasties at 76 operations with no operative mortality and with septic complications in only two patients (4 percent). Median (range) follow-up was 49.5 (1-182) months. Nineteen patients (36 percent) required a second operation for Crohn's disease between 1 and 57 months after first strictureplasty. Most symptomatic recurrence was caused by new segments of stricturing or perforating disease, and recurrence of Crohn's disease was noted at only nine strictureplasty sites (3.7 percent) in four patients. Seven patients (13 percent) required a third operation for Crohn's disease. Patients undergoing strictureplasty alone were no more likely to require reoperation than those who had a concomitant resection at the first procedure (X2 = 0.619, P > 0.2). The reoperation rates after first and second operations were similar (X2 = 0.021, P > 0.2). Minimal surgery does not appear to lead to an accelerated or additional need for subsequent operation. Strictureplasty provides a safe, effective and rapid procedure to restore patients to good health while preserving the intestine and may be recommended for carefully selected strictures as an adjunct to conventional excisional surgical treatment.

摘要

狭窄成形术为梗阻性克罗恩病的治疗扩展了手术选择。在15年期间,52例患者接受了76次手术,共进行了241次狭窄成形术,无手术死亡病例,仅2例患者(4%)出现感染并发症。中位(范围)随访时间为49.5(1 - 182)个月。19例患者(36%)在首次狭窄成形术后1至57个月因克罗恩病需要再次手术。大多数症状复发是由新的狭窄或穿孔性病变节段引起的,仅在4例患者的9个狭窄成形术部位(3.7%)发现克罗恩病复发。7例患者(13%)因克罗恩病需要第三次手术。单纯接受狭窄成形术的患者与首次手术时同时进行切除术的患者相比,再次手术的可能性并无增加(X2 = 0.619,P > 0.2)。首次和第二次手术后的再次手术率相似(X2 = 0.021,P > 0.2)。微创手术似乎不会导致后续手术需求加速或增加。狭窄成形术提供了一种安全、有效且快速的方法,可使患者恢复健康,同时保留肠道,对于精心挑选的狭窄病例,可作为传统切除性手术治疗的辅助方法推荐使用。

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