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狭窄成形术是十二指肠克罗恩病手术治疗中的一种有效选择。

Strictureplasty is an effective option in the operative management of duodenal Crohn's disease.

作者信息

Worsey M J, Hull T, Ryland L, Fazio V

机构信息

Cleveland Clinic Foundation, Ohio 44195, USA.

出版信息

Dis Colon Rectum. 1999 May;42(5):596-600. doi: 10.1007/BF02234132.

Abstract

INTRODUCTION

Duodenal Crohn's disease requiring surgery has traditionally been managed with a bypass procedure. We compared our experience with duodenal strictureplasty with this traditional approach.

METHODS

Records of patients operated on for duodenal Crohn's disease since 1980 were retrospectively reviewed. Patients having strictureplasty or bypass were compared with regard to demographics, indications, complications, and outcome.

RESULTS

Since 1980, 34 patients were operated on for duodenal Crohn's disease. Mean age was 38.9 (range, 16-68) years, and 20 of 34 patients were females, with no significant differences between operative groups. Obstruction was the presenting symptom in 33 of 34 patients, and all had strictures. The basis for diagnosis of duodenal Crohn's disease was macroscopic appearance and the presence of Crohn's elsewhere in 29 of 34 patients, with only 5 of 34 having either duodenal or contiguous antral granulomas. Thirty-seven strictures were present in the 34 patients; 24 were in the proximal duodenum (8 strictureplasty, 16 bypass), 9 were in the midduodenum (4 strictureplasty, 5 bypass), and 4 were in the distal duodenum (3 strictureplasty, 1 bypass). Bypass was performed in 21 patients, with two operative complications, and at a mean follow-up of 8 years, 1 of 21 patients required reoperation for recurrent disease. Strictureplasty was performed in 13 patients, with two operative complication, and at a mean follow-up of 3.6 years, 1 patient required reoperation for recurrence also. Vagotomy was performed in 16 of 21 bypasses and 7 of 13 strictureplasties.

CONCLUSIONS

Although follow-up is shorter, strictureplasty is a safe and effective operation for duodenal Crohn's disease and should be considered when feasible.

摘要

引言

传统上,需要手术治疗的十二指肠克罗恩病采用旁路手术进行处理。我们将十二指肠狭窄成形术的经验与这种传统方法进行了比较。

方法

回顾性分析自1980年以来接受十二指肠克罗恩病手术患者的记录。对接受狭窄成形术或旁路手术的患者在人口统计学、手术指征、并发症及预后方面进行比较。

结果

自1980年以来,34例患者接受了十二指肠克罗恩病手术。平均年龄为38.9岁(范围16 - 68岁),34例患者中有20例为女性,各手术组之间无显著差异。34例患者中有33例以梗阻为首发症状,且均有狭窄。十二指肠克罗恩病的诊断依据为肉眼外观以及34例患者中29例在其他部位存在克罗恩病,34例中仅有5例有十二指肠或相邻胃窦部肉芽肿。34例患者共有37处狭窄;24处在十二指肠近端(8例行狭窄成形术,16例行旁路手术),9处在十二指肠中部(4例行狭窄成形术,5例行旁路手术),4处在十二指肠远端(3例行狭窄成形术,1例行旁路手术)。21例患者接受了旁路手术,有2例手术并发症,平均随访8年时,21例中有1例因疾病复发需要再次手术。13例患者接受了狭窄成形术,有2例手术并发症,平均随访3.6年时,也有1例患者因复发需要再次手术。21例旁路手术中有16例、13例狭窄成形术中有7例同时进行了迷走神经切断术。

结论

尽管随访时间较短,但狭窄成形术对于十二指肠克罗恩病是一种安全有效的手术,可行时应予以考虑。

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