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狭窄成形术治疗梗阻性克罗恩病的十年经验

Ten-year experience of strictureplasty for obstructive Crohn's disease.

作者信息

Dehn T C, Kettlewell M G, Mortensen N J, Lee E C, Jewell D P

机构信息

Department of Surgery, John Radcliffe Hospital, Oxford, UK.

出版信息

Br J Surg. 1989 Apr;76(4):339-41. doi: 10.1002/bjs.1800760407.

Abstract

Strictureplasty is controversial in the management of obstructive Crohn's disease. Only a small proportion of patients undergoing surgery for obstructive Crohn's disease are suitable for strictureplasty. Lesions which are most amenable for this procedure are short, fibrous strictures. Over a 10-year period 24 patients have undergone 30 operations at which 86 strictureplasties were performed. The median follow-up has been 40 (range 4-112) months. No leaks or fistulae arose from the strictureplasties. The median weight gain 3 months postoperatively was +4.0 kg. Four patients subsequently required a further 13 strictureplasty procedures, between 12 and 36 (median 18) months after the initial operation; all but one of the previous strictureplasties were patent. Thirteen patients have been symptom free following surgery, four have required further medical therapy for recurrent Crohn's disease and three have sustained episodes of self-limiting intestinal colic. Strictureplasty is a safe and effective procedure in selected patients undergoing surgery for obstructive Crohn's disease.

摘要

狭窄成形术在梗阻性克罗恩病的治疗中存在争议。仅一小部分因梗阻性克罗恩病接受手术的患者适合行狭窄成形术。最适合该手术的病变是短的纤维性狭窄。在10年期间,24例患者接受了30次手术,共进行了86次狭窄成形术。中位随访时间为40(4 - 112)个月。狭窄成形术未出现渗漏或瘘管。术后3个月体重增加的中位数为 +4.0 kg。4例患者随后在初次手术后12至36(中位18)个月需要再行13次狭窄成形术;除1例之外,之前所有的狭窄成形术部位均通畅。13例患者术后无症状,4例因克罗恩病复发需要进一步药物治疗,3例有自限性肠痉挛发作。对于因梗阻性克罗恩病接受手术的特定患者,狭窄成形术是一种安全有效的手术。

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