Spieker S, Jentgens C, Boose A, Dichgans J
Department of Neurology, University of Tübingen, Germany.
Electroencephalogr Clin Neurophysiol. 1995 Dec;97(6):326-31. doi: 10.1016/0924-980x(95)00208-3.
We have developed a method of long-term EMG recording that has proven suitable for the quantification of pathological tremor. In the present paper we show that the principal parameters of the method (tremor occurrence, tremor intensity, tremor frequency) are highly reproducible and that the method is specific and sensitive for detection of pathological tremor. Twelve patients with essential tremor (ET) and 13 patients with Parkinson's disease (PD) were recorded repeatedly on 3 successive days. For each patient group and for each parameter the intersubject variability was much larger than the intersubject variability. The intraclass correlation coefficient "R" was in the order of 0.9 for each parameter and the mean of Pearson's correlation coefficient between successive days was also approximately 0.9. Recordings from normal controls demonstrated that the method's specificity for pathological tremor is 94.1% and its sensitivity is 96%.
我们开发了一种长期肌电图记录方法，该方法已被证明适用于病理性震颤的量化。在本文中，我们表明该方法的主要参数（震颤发生率、震颤强度、震颤频率）具有高度可重复性，并且该方法对病理性震颤的检测具有特异性和敏感性。对12例特发性震颤（ET）患者和13例帕金森病（PD）患者连续3天进行重复记录。对于每个患者组和每个参数，个体间的变异性远大于个体内的变异性。每个参数的组内相关系数“R”约为0.9，连续几天之间的皮尔逊相关系数平均值也约为0.9。正常对照的记录表明，该方法对病理性震颤的特异性为94.1%，敏感性为96%。
