Wilkins M R, Williams K L
School of Biological Sciences, Macquarie University, Sydney, N.S.W., Australia.
Experientia. 1995 Dec 18;51(12):1189-96. doi: 10.1007/BF01944736.
In this review, we detail the current understanding of the extracellular matrix (ECM) of the migratory slug phase of the cellular slime mould, Dictyostelium discoideum. We describe some structural and non-structural molecules which comprise the ECM, and how these molecules reflect both plant and animal ECM systems. We also describe zones of the multicellular slug that are known to make ECM components, including the role of the prestalk cells and the slug epithelium-like layer. Finally, we review the contributions of studies on mutants to our understanding of the ECM of D. discoideum, and relate this to differentiation and development in more complex eukaryotic systems.
在本综述中,我们详细阐述了目前对细胞黏菌盘基网柄菌迁移期蛞蝓阶段细胞外基质(ECM)的理解。我们描述了构成ECM的一些结构和非结构分子,以及这些分子如何反映植物和动物的ECM系统。我们还描述了已知能产生ECM成分的多细胞蛞蝓的区域,包括前柄细胞和蛞蝓上皮样层的作用。最后,我们综述了对突变体的研究对我们理解盘基网柄菌ECM的贡献,并将其与更复杂真核系统中的分化和发育联系起来。