慢性活动性肝炎中HLA - DRW4频率增加。
Increased frequency of HLA-DRW4 in chronic active hepatitis.
作者信息
Williams R M, Martin S, Falchuk K R, Trey C, Dubey D P, Cannady W G, Fitzpatrick D, Noreen H, Dupont B, Yunis E J
出版信息
Vox Sang. 1978;35(6):366-9. doi: 10.1111/j.1423-0410.1978.tb02948.x.
Abstract
HLA-A, B, C and DRw typing was performed on peripheral blood lymphocytes of 17 adults with the diagnosis of chronic active hepatitis made by liver biopsy as the only criterion for study. An increase in the frequency of HLA-DRw4 (71 vs. 24%, p less than 0.005) was observed, but there was no increased frequency of HLA-A1, B8 or any other HLA locus specificity.
摘要
以肝活检作为唯一研究标准，对17例诊断为慢性活动性肝炎的成年患者的外周血淋巴细胞进行了HLA - A、B、C和DRw分型。观察到HLA - DRw4频率增加（71%对24%，p小于0.005），但HLA - A1、B8或任何其他HLA位点特异性的频率没有增加。
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