Necrotizing sarcoid granulomatosis: computed tomography and pathologic findings.

OBJECTIVE

To describe the CT findings and corresponding pathological findings of necrotizing sarcoid granulomatosis (NSG).

MATERIALS AND METHODS

We reviewed the high-resolution CT and macroscopic and histologic findings in three pathologically proven cases of NSG.

RESULTS

The CT findings consisted of one case each with single nodule, multiple nodules, and parenchymal opacification. The abnormalities were peribronchovascular or subpleural in distribution. Histologically, all patients had sarcoid-like granulomas with central necrosis and granulomatous vasculitis. The CT findings correlated closely with the gross pathologic findings.

CONCLUSION

We conclude that the CT manifestations of NSG reflect the variable macroscopic pathologic findings.