• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Culture microtitration: a sensitive method for quantifying Leishmania infantum in tissues of infected mice.培养微量滴定法:一种用于定量检测感染小鼠组织中婴儿利什曼原虫的灵敏方法。
Antimicrob Agents Chemother. 1995 Sep;39(9):2167-8. doi: 10.1128/AAC.39.9.2167.
2
Influence of the host and parasite strain in a mouse model of visceral Leishmania infantum infection.宿主和寄生虫菌株在内脏利什曼原虫婴儿感染小鼠模型中的影响。
FEMS Immunol Med Microbiol. 1998 Jul;21(3):231-9. doi: 10.1111/j.1574-695X.1998.tb01170.x.
3
Real-time PCR as a new tool for quantifying Leishmania infantum in liver in infected mice.实时荧光定量PCR作为一种用于定量感染小鼠肝脏中婴儿利什曼原虫的新工具。
Clin Diagn Lab Immunol. 2001 Jul;8(4):828-31. doi: 10.1128/CDLI.8.4.828-831.2001.
4
Lipid formulations of amphotericin b in the treatment of experimental visceral leishmaniasis due to Leishmania infantum.两性霉素B脂质制剂治疗婴儿利什曼原虫引起的实验性内脏利什曼病。
Trans R Soc Trop Med Hyg. 1996 Sep-Oct;90(5):574-7. doi: 10.1016/s0035-9203(96)90330-2.
5
Therapeutic effect of reference antileishmanial agents in murine visceral leishmaniasis due to Leishmania infantum.参比抗利什曼原虫药物对婴儿利什曼原虫所致小鼠内脏利什曼病的治疗效果。
Ann Trop Med Parasitol. 1996 Jun;90(3):295-302. doi: 10.1080/00034983.1996.11813054.
6
Efficacy of aminosidine administered alone or in combination with meglumine antimoniate for the treatment of experimental visceral leishmaniasis caused by Leishmania infantum.单独使用氨基糖苷或与葡甲胺锑酸盐联合使用治疗婴儿利什曼原虫引起的实验性内脏利什曼病的疗效。
J Antimicrob Chemother. 1997 Aug;40(2):287-9. doi: 10.1093/jac/40.2.287.
7
Experimental evaluation of second-line oral treatments of visceral leishmaniasis caused by Leishmania infantum.婴儿利什曼原虫引起的内脏利什曼病二线口服治疗的实验评估
Antimicrob Agents Chemother. 1999 Jan;43(1):172-4. doi: 10.1128/AAC.43.1.172.
8
The Inflammatory Effects of Dietary Lipids Regulate Growth of Parasites during Visceral Leishmaniasis.膳食脂质的炎症效应调节内脏利什曼病期间寄生虫的生长。
mSphere. 2021 Aug 25;6(4):e0042321. doi: 10.1128/mSphere.00423-21. Epub 2021 Jul 14.
9
T-cell populations and cytokine expression are impaired in thymus and spleen of protein malnourished BALB/c mice infected with Leishmania infantum.感染婴儿利什曼原虫的蛋白质营养不良BALB/c小鼠的胸腺和脾脏中,T细胞群体和细胞因子表达受损。
PLoS One. 2014 Dec 23;9(12):e114584. doi: 10.1371/journal.pone.0114584. eCollection 2014.
10
Protection mediated by chemokine CXCL10 in BALB/c mice infected by Leishmania infantum.趋化因子CXCL10介导的对感染婴儿利什曼原虫的BALB/c小鼠的保护作用。
Mem Inst Oswaldo Cruz. 2017 Aug;112(8):561-568. doi: 10.1590/0074-02760160529.

引用本文的文献

1
Efficacy of vaccines based on chimeric or multiepitope antigens for protection against visceral leishmaniasis: A systematic review.基于嵌合或多表位抗原的疫苗预防内脏利什曼病的疗效:一项系统评价。
PLoS Negl Trop Dis. 2024 Dec 31;18(12):e0012757. doi: 10.1371/journal.pntd.0012757. eCollection 2024 Dec.
2
Enhancing Control of Infection: A Multi-Epitope Nanovaccine for Durable T-Cell Immunity.增强感染控制:一种用于持久T细胞免疫的多表位纳米疫苗。
Animals (Basel). 2024 Feb 13;14(4):605. doi: 10.3390/ani14040605.
3
Eugenol-Rich Essential Oil from : In Vitro and In Vivo Potentialities against .来自富含丁香酚的精油:体外和体内抗……的潜力
Pharmaceuticals (Basel). 2023 Dec 29;17(1):64. doi: 10.3390/ph17010064.
4
A Tailored Approach to Leishmaniases Vaccination: Comparative Evaluation of the Efficacy and Cross-Protection Capacity of DNA vs. Peptide-Based Vaccines in a Murine Model.一种针对利什曼病的定制化疫苗接种方法:在小鼠模型中评估 DNA 与肽基疫苗的疗效和交叉保护能力的比较。
Int J Mol Sci. 2023 Aug 2;24(15):12334. doi: 10.3390/ijms241512334.
5
Zinc and Manganese Imbalances in BALB/c Mice Experimentally Infected with Leishmania (Leishmania) amazonensis.实验感染利什曼原虫(Leishmania)亚马逊巴贝斯虫后 BALB/c 小鼠的锌和锰失衡。
Acta Parasitol. 2023 Jun;68(2):447-452. doi: 10.1007/s11686-023-00666-1. Epub 2023 Mar 8.
6
The therapeutic effect of larval saliva and hemolymph of Lucilia sericata on the treatment of Leishmania major lesion in BALB/c mice946.丝光绿蝇幼虫唾液和血液对治疗 BALB/c 小鼠大内脏利什曼原虫病变的疗效946.
Parasit Vectors. 2023 Feb 16;16(1):72. doi: 10.1186/s13071-023-05660-0.
7
Effects of negative air ions (NAIs) on Leishmania major: A novel tool for treatment of zoonotic cutaneous leishmaniasis (ZCL).负氧离子(NAIs)对利什曼原虫的影响:一种治疗动物源性皮肤利什曼病(ZCL)的新工具。
PLoS One. 2022 Sep 8;17(9):e0274124. doi: 10.1371/journal.pone.0274124. eCollection 2022.
8
A new immunochemotherapy schedule for visceral leishmaniasis in a hamster model.一种新的免疫化学疗法方案用于仓鼠内脏利什曼病模型。
Parasitol Res. 2022 Oct;121(10):2849-2860. doi: 10.1007/s00436-022-07628-y. Epub 2022 Aug 23.
9
A Mouse Model of Ulcerative Cutaneous Leishmaniasis by to Investigate Infection, Pathogenesis, Immunity, and Therapeutics.一种用于研究感染、发病机制、免疫和治疗方法的溃疡性皮肤利什曼病小鼠模型。
Front Microbiol. 2022 Jun 13;13:907631. doi: 10.3389/fmicb.2022.907631. eCollection 2022.
10
UBC1 in Metacyclic Promastigotes from , a Vaccine Candidate for Zoonotic Visceral Leishmaniasis.来自[具体来源]的循环前期前鞭毛体中的UBC1,一种人兽共患内脏利什曼病的候选疫苗。
Vaccines (Basel). 2022 Feb 3;10(2):231. doi: 10.3390/vaccines10020231.

本文引用的文献

1
Leishmaniasis and AIDS co-infection: the Spanish example.利什曼病与艾滋病合并感染:以西班牙为例。
Parasitol Today. 1994 Apr;10(4):160-3. doi: 10.1016/0169-4758(94)90270-4.
2
Advantages of measuring changes in the number of viable parasites in murine models of experimental cutaneous leishmaniasis.在实验性皮肤利什曼病小鼠模型中测量活寄生虫数量变化的优势。
Infect Immun. 1983 Mar;39(3):1087-94. doi: 10.1128/iai.39.3.1087-1094.1983.
3
A limiting dilution assay for quantifying Leishmania major in tissues of infected mice.一种用于定量感染小鼠组织中硕大利什曼原虫的有限稀释分析方法。
Parasite Immunol. 1985 Sep;7(5):545-55. doi: 10.1111/j.1365-3024.1985.tb00098.x.

培养微量滴定法:一种用于定量检测感染小鼠组织中婴儿利什曼原虫的灵敏方法。

Culture microtitration: a sensitive method for quantifying Leishmania infantum in tissues of infected mice.

作者信息

Buffet P A, Sulahian A, Garin Y J, Nassar N, Derouin F

机构信息

Laboratoire de Parasitologie-Mycologie, Faculté de Médecine Lariboisière Saint-Louis, Paris, France.

出版信息

Antimicrob Agents Chemother. 1995 Sep;39(9):2167-8. doi: 10.1128/AAC.39.9.2167.

DOI:10.1128/AAC.39.9.2167
PMID:8540741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC162906/
Abstract

We developed a microtitration method to determine the parasite burdens in homogenized organs of mice infected with Leishmania infantum. This method proved more sensitive than direct enumeration of amastigotes in stained organs, was appropriate for describing the kinetics of infection, and can be considered for physiopathological or pharmaceutical experimental studies.

摘要

我们开发了一种微量滴定法来测定感染婴儿利什曼原虫的小鼠匀浆器官中的寄生虫负荷。该方法比直接计数染色器官中的无鞭毛体更敏感,适用于描述感染动力学,可用于生理病理学或药物实验研究。