Spence S A, Taylor D G, Hirsch S R
Academic Department of Psychiatry, Charing Cross Hospital, London, England.
J R Soc Med. 1995 Nov;88(11):637-8. doi: 10.1177/014107689508801109.
Secondary causes of depression are legion, and must always be considered in patients presenting with features atypical of primary idiopathic depressive disorder. The case described is that of a middle-aged woman presenting initially with a major depressive disorder who was subsequently found to have a craniopharyngioma, leading to a revised diagnosis of mood disorder due to the tumour. Some features of the presentation might have led to earlier diagnosis had their localizing significance been recognized. Diencephalic lesions should always be considered in patients presenting with the hypersomnic-hyperphagic variant of depressive disorder.
抑郁症的继发性病因众多，对于那些具有原发性特发性抑郁症非典型特征的患者，必须始终予以考虑。本文所述病例为一名中年女性，最初表现为重度抑郁症，随后被发现患有颅咽管瘤，导致诊断修正为肿瘤所致心境障碍。如果认识到其定位意义，该病例呈现的一些特征可能会促使更早做出诊断。对于表现为抑郁障碍的嗜睡-贪食变体的患者，应始终考虑间脑病变。
