Gharpure V S, Devine S M, Holland H K, Geller R B, O'Toole K, Wingard J R
Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
Bone Marrow Transplant. 1995 Nov;16(5):715-6.
Thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) have been observed after bone marrow transplantation (BMT), typically occurring 1-6 months following BMT. We describe two patients who developed TTP very early after BMT while receiving intravenous FK506. They were treated with platelet support and plasma exchange (PE) using either fresh frozen plasma (FFP) or cryosupernatant fraction of plasma (CFP), resulting in remission of TTP activity.
骨髓移植（BMT）后曾观察到血栓性血小板减少性紫癜（TTP）和溶血性尿毒症综合征（HUS），通常发生在BMT后的1 - 6个月。我们描述了两名在接受静脉注射FK506时于BMT后很早便发生TTP的患者。他们接受了血小板支持治疗，并使用新鲜冰冻血浆（FFP）或血浆冷上清部分（CFP）进行血浆置换（PE），从而使TTP活动得到缓解。
