Rodríguez R M, Aldrey J M, Pumar J M, Lema M, Noya M
Servicio de Neurología, Hospital General de Galicia Clínico Universitario, Santiago de Compostela.
Rev Neurol. 1995 Jan-Feb;23(119):59-61.
The estimation of the size of the structures of the temporal lobe using magnetic resonance (MR) can be of assistance when diagnosing early degenerative dementia. We have carried out a survey on 17 patients with Alzheimer type dementia (ATD). They were classified in clinical stages according to the Reisberg global deterioration scale. As diagnostic criteria for ATD we used those developed by DSM-III-R and NINCDS-ADRDA. We carried out axial sequences of 10 mm thickness in protonic density and in T2, and crown sequences of 5mm in T1 perpendicular to the axis of the hypofield. We selected the crown incisions at the level of the interpeduncular cistern. We determined the areas of the temporal lobe, hypocampus and ventricular and two linear measurements (the interhypocampus distance and the maximum transverse diameter between internal layers of the craneum). The images were processed by means of a computer programme. The average area of both hypofields in patients at stages 3-5 on the Reisberg scale was 378.6 +/- 86.1 mm2 and in stages 6-7 was of 364.7 +/- 62.2 mm2. The average area of both temporal lobes in patients at stages 3-5 was of 2,177.03 +/- 411.4 mm2 and in stages 6-7, was of 1,945.0 +/- 303.3 mm2. The shrinkage in size of the temporal lobe and the hypocampus in patients with Alzheimer's disease was not found to be related with the degree of dementia.
在诊断早期退行性痴呆时，使用磁共振（MR）估计颞叶结构的大小可能会有所帮助。我们对17例阿尔茨海默型痴呆（ATD）患者进行了一项调查。根据雷斯伯格整体衰退量表，将他们分为临床阶段。作为ATD的诊断标准，我们采用了由DSM-III-R和NINCDS-ADRDA制定的标准。我们在质子密度和T2序列中进行了10毫米厚的轴位扫描，并在垂直于低场轴的T1序列中进行了5毫米厚的冠状扫描。我们选择了脚间池水平的冠状切口。我们确定了颞叶、海马和脑室的面积以及两项线性测量值（海马间距离和颅骨内层之间的最大横径）。图像通过计算机程序进行处理。雷斯伯格量表3-5期患者双侧低场的平均面积为378.6 +/- 86.1平方毫米，6-7期为364.7 +/- 62.2平方毫米。3-5期患者双侧颞叶的平均面积为2,177.03 +/- 411.4平方毫米，6-7期为1,945.0 +/- 303.3平方毫米。未发现阿尔茨海默病患者颞叶和海马的大小缩小与痴呆程度相关。
