Seidenari S, Manzini B M, Schiavi M E, Motolese A
Department of Dermatology, University of Modena, Italy.
Contact Dermatitis. 1995 Aug;33(2):118-22. doi: 10.1111/j.1600-0536.1995.tb00512.x.
5 non-disperse azo dyes, used for colouring natural fibers, were added to the standard patch test series, as 5% pet. preparations. 1814 consecutive patients attending the patch test clinic were patch tested, of whom 16 (0.88%) reacted to the newly added dyes: 8 to Direct Orange 34, 5 to Acid Yellow 61, 2 to Acid Red 359 and 1 to Acid Red 118. On the basis of clinical history and results of patch tests with pieces of fabrics, contact sensitization to non-disperse azo dyes seemed to be related to the appearance of skin lesions at least in 8 subjects. We conclude that systematic exploration of the sensitizing potential of textile dyes, selected after careful investigation, can provide additional information on the frequency of occurrence of textile dye dermatitis, supporting individual investigation in sensitized subjects.
5种用于天然纤维染色的非分散性偶氮染料，以5%的凡士林制剂形式被添加到标准斑贴试验系列中。1814名连续到斑贴试验门诊就诊的患者接受了斑贴试验，其中16人（0.88%）对新添加的染料有反应：8人对直接橙34有反应，5人对酸性黄61有反应，2人对酸性红359有反应，1人对酸性红118有反应。根据临床病史和用织物片进行斑贴试验的结果，至少在8名受试者中，对非分散性偶氮染料的接触致敏似乎与皮肤病变的出现有关。我们得出结论，对经过仔细研究挑选出的纺织染料致敏潜力进行系统探究，可以提供关于纺织染料皮炎发生频率的更多信息，有助于对致敏个体进行调查。
