Vilnius University Antakalnis Hospital Allergy Centre, Vilnius, Lithuania.
Contact Dermatitis. 2013 Feb;68(2):65-75. doi: 10.1111/cod.12001.
Several disperse dyes (DDs) are still considered to be the most important allergens in textile dermatitis, but there are sparse data about their current use in textiles. The aim of this review was to evaluate published studies and reports on contact allergy to DDs published in PubMed during the last 22 years (1990-2012). Prevalence data are provided by study and by dye, as well as by the described clinical peculiarities of DD dermatitis. We reviewed 54 studies. In total, 26 DDs were tested. The average prevalence in screening studies was >1% for Disperse Blue 106, Disperse Blue 124, and Disperse Orange 3. There is a lack of data on patch testing with Disperse Blue 26, Disperse Blue 102, Disperse Orange 37, Disperse Orange 149, Disperse Yellow 23 and Disperse Yellow 49, which are listed as allergens by the EU Commission. It is necessary to check the purity and identity of dyes used for patch testing, confirm the clinical relevance of positive reactions by patch testing with suspected textiles, and, if the results are positive, determine the culprit dye.
有几种分散染料（DDs）仍然被认为是导致纺织物皮炎的最重要的过敏原，但关于它们在纺织品中的当前用途的数据却很少。本综述的目的是评估过去 22 年（1990-2012 年）期间在 PubMed 上发表的关于接触性 DD 过敏的研究和报告。通过研究和染料以及 DD 皮炎的描述性临床特征提供了流行率数据。我们共审查了 54 项研究。总共测试了 26 种 DD。在筛选研究中，Disperse Blue 106、Disperse Blue 124 和 Disperse Orange 3 的平均流行率>1%。缺乏关于Disperse Blue 26、Disperse Blue 102、Disperse Orange 37、Disperse Orange 149、Disperse Yellow 23 和 Disperse Yellow 49 等的斑贴试验数据，这些物质被欧盟委员会列为过敏原。有必要检查斑贴试验所用染料的纯度和身份，通过对疑似纺织品进行斑贴试验来确认阳性反应的临床相关性，如果结果为阳性，则确定罪魁祸首染料。
