Iglesias Cubero G, Rodriguez Reguero J J, Terrados N, González V, Barriales R, Cortina A
Servicio de Cardiologia, Hospital Central de Asturias, Oviedo, Spain.
Int J Sports Med. 1995 Oct;16(7):475-7. doi: 10.1055/s-2007-973040.
Aldosterone has been associated with the development of cardiac hypertrophy and a correlation has been found between levels of aldosterone and the degree of cardiac hypertrophy in hypertensive patients. Our study aimed to test the relation between physiologic cardiac hypertrophy and serum aldosterone in a group of highly trained cyclists. Determination of the left ventricular mass index (LVMI) was performed in a group of 40 professional cyclists by using Devereux's formula with correction for body surface area. After an overnight fast, blood samples were collected and serum aldosterone levels were measured using RIA. LVMI and serum aldosterone were intercorrelated using linear regression analysis. Twenty-three of the 40 cyclists (58%) presented an LVMI > 130 g.m-1 and the other 17 subjects (42%) presented an LVMI < 130 g.m-1. Serum aldosterone levels did not correlate with LVMI in either of the groups (LVMI > 130 g.m-1, r = -0.089; LVMI < 130 g.m-1, r = 0.146). The lack of correlation of this hypertrophy with serum aldosterone levels suggests that physiologic hypertrophy of the athlete's heart could be caused by a different stimulus to that seen in pathologic hypertrophy of hypertensives.
醛固酮与心脏肥大的发生有关，并且在高血压患者中已发现醛固酮水平与心脏肥大程度之间存在相关性。我们的研究旨在测试一组训练有素的自行车运动员的生理性心脏肥大与血清醛固酮之间的关系。通过使用Devereux公式并校正体表面积，对一组40名职业自行车运动员进行左心室质量指数（LVMI）的测定。过夜禁食后，采集血样并使用放射免疫分析法测量血清醛固酮水平。使用线性回归分析对LVMI和血清醛固酮进行相互关联分析。40名自行车运动员中有23名（58%）的LVMI>130 g·m⁻¹，其他17名受试者（42%）的LVMI<130 g·m⁻¹。两组中血清醛固酮水平均与LVMI无相关性（LVMI>130 g·m⁻¹，r = -0.089；LVMI<130 g·m⁻¹，r = 0.146）。这种肥大与血清醛固酮水平缺乏相关性表明，运动员心脏的生理性肥大可能是由与高血压患者病理性肥大不同的刺激引起的。
