Ramasubramanian T S, Wei T F, Oldham A K, Golden J W
Department of Biology, Texas A&M University, College Station 77843-3258, USA.
J Bacteriol. 1996 Feb;178(3):922-6. doi: 10.1128/jb.178.3.922-926.1996.
The Anabaena sp. strain PCC 7120 ntcA gene showed multiple transcripts with different 5' ends. The relative abundance of transcripts varied in response to nitrogen availability. The ntcA product, NtcA, showed binding to the promoter region of its own gene. The binding site mapped to a region between the transcription start site used under nitrogen-replete conditions and the start sites used under nitrogen-limiting conditions, suggesting that NtcA regulates its own expression.
鱼腥藻属PCC 7120菌株的ntcA基因显示出具有不同5'末端的多个转录本。转录本的相对丰度随氮供应情况而变化。ntcA产物NtcA显示出与自身基因的启动子区域结合。结合位点定位于氮充足条件下使用的转录起始位点和氮限制条件下使用的起始位点之间的区域,这表明NtcA调节其自身的表达。