一名患有马凡综合征的患者接受氧疗治疗阻塞性睡眠呼吸暂停低通气综合征。

Obstructive sleep hypopnea syndrome in a patient with Marfan syndrome treated with oxygen therapy.

作者信息

Verbraecken J A, Willemen M, De Cock W, Coen E, Van de Heyning P, De Backer W

机构信息

Department of Respiratory Medicine, University Hospital of Antwerp, Belgium.

出版信息

Respiration. 1995;62(6):355-8. doi: 10.1159/000196480.

DOI:10.1159/000196480

PMID:8552869

Abstract

A patient with Marfan's syndrome and obstructive sleep hypopnea syndrome is reported. She had complained about insomnia, tiredness and hypersomnolence lasting 2 years. A complete nightly polysomnography revealed 94 obstructive hypopneas (the hypopnea index was 12.85) and no obstructive apneas. Presumably an increased laxity of the pharyngeal wall was responsible for the phenomenon. A therapy with CPAP was started, but was not tolerated by the patient. Oxygen therapy on the other hand turned out to be effective and well tolerated.

摘要

报告了一名患有马凡氏综合征和阻塞性睡眠呼吸暂停低通气综合征的患者。她抱怨失眠、疲倦和嗜睡持续了2年。完整的夜间多导睡眠图显示有94次阻塞性呼吸不足（呼吸不足指数为12.85），无阻塞性呼吸暂停。推测咽壁松弛度增加是导致该现象的原因。开始了持续气道正压通气（CPAP）治疗，但患者无法耐受。另一方面，氧疗被证明是有效的且耐受性良好。